Liposomes:a promising carrier for respiratory syncytial virus therapeutics


Introduction: Human respiratory syncytial virus (RSV) is a common respiratory virus that causes severe lower respiratory tract infection in infants, children and aged adults. Currently, there is no active prophylaxis present in the market for RSV infection; however, there are over a dozen compounds being tested in the laboratory as well as clinical trials. To increase the efficiency and safety of these therapeutics, there is a need for delivery vehicles. Areas covered: Liposomes can be used for delivering anti-RSV agents with the advantage of modulating and eliciting the desired adjuvant effect by the different combination of lipids. This review discusses the promising application of liposome for anti-RSV therapeutics. Expert opinion: Liposomes are attracting attention for delivery of pulmonary therapeutics, since they offer compatibility for delivering drugs, vaccines and other therapeutic molecules. Variation in liposome size and composition gives flexibility for the amount and number of deliverables, whilst targeted delivery with the capability for immunomodulation makes liposomes a promising candidate for RSV therapeutic applications.

Divisions: College of Health & Life Sciences > Aston Pharmacy School
College of Health & Life Sciences > Chronic and Communicable Conditions
College of Health & Life Sciences
Additional Information: This is an Accepted Manuscript of an article published by Taylor & Francis Group in Expert Opinion on Drug Delivery on 7 Aug 2019, available online at:
Publication ISSN: 1744-7593
Last Modified: 29 Nov 2023 12:31
Date Deposited: 03 Sep 2019 08:22
Full Text Link: 10.1080/17425247.2019.1652268
Related URLs: https://www.tan ... rnalCode=iedd20 (Publisher URL)
http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Review article
Published Date: 2019-08-07
Accepted Date: 2019-08-01
Authors: Joshi, Sameer
Bawage, Swapnil
Tiwari, Pooja
Kirby, Daniel
Perrie, Yvonne
Dennis, Vida
Singh, Shree R



Version: Accepted Version

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