Jaggi, V., Leaper, M.C. and Ingham, A.J. (2015). Measuring the flow properties of small powder samples using an avalanche tester. Drying Technology, 34 (6), pp. 723-728.
Abstract
The feasibility of using a small-scale avalanche tester to measure the flow properties of pharmaceutical lactose powders was examined. The modes of behaviour observed in larger systems were displayed and showed a clear distinction between angular, free-flowing particles and more spherical particles of similar flow characteristics. Angular Lactohale LH100 particles showed slumping behaviour at a rotational frequency of 0.33Hz which disappeared at higher frequencies. Spherical lactose powder with a similar flow function to LH100 only showed rolling behaviour under the same conditions, as did more cohesive powders LH200 and LH300. Further investigation of the LH100 data using Fast Fourier analysis showed that the slumping frequency was 1/10th of the rotational frequency.
| Publication DOI: | https://doi.org/10.1080/07373937.2015.1072093 |
|---|---|
| Divisions: | College of Engineering & Physical Sciences > School of Infrastructure and Sustainable Engineering > Chemical Engineering & Applied Chemistry College of Engineering & Physical Sciences > Aston Institute of Materials Research (AIMR) College of Health & Life Sciences > Aston Pharmacy School College of Health & Life Sciences College of Health & Life Sciences > Chronic and Communicable Conditions |
| Additional Information: | This is an Accepted Manuscript of an article published by Taylor & Francis in Drying Technology on 27/7/15, available online: http://www.tandfonline.com/10.1080/07373937.2015.1072093 |
| Uncontrolled Keywords: | pharmaceuticals,powder technology,rotary drying,General Chemical Engineering,Physical and Theoretical Chemistry |
| Publication ISSN: | 1532-2300 |
| Last Modified: | 17 Dec 2024 08:09 |
| Date Deposited: | 19 Aug 2019 10:07 |
| Full Text Link: | |
| Related URLs: |
http://www.scop ... tnerID=8YFLogxK
(Scopus URL) |
PURE Output Type: | Article |
| Published Date: | 2015-07-27 |
| Published Online Date: | 2015-07-27 |
| Accepted Date: | 2015-07-01 |
| Authors: |
Jaggi, V.
Leaper, M.C. Ingham, A.J. |
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)