Tailoring treatment to the individual in type 2 diabetes practical guidance from the Global Partnership for Effective Diabetes Management

Abstract

Good glycaemic control continues to be the most effective therapeutic manoeuvre to reduce the risk of development and/or progression of microvascular disease, and therefore remains the cornerstone of diabetes management despite recent scepticism about tight glucose control strategies. The impact on macrovascular complications is still a matter of debate, and so glycaemic control strategies should be placed in the context of multifactorial intervention to address all cardiovascular risk factors. Approaches to achieve glycaemic targets should always ensure patient safety, and results from recent landmark outcome studies support the need for appropriate individualisation of glycaemic targets and of the means to achieve these targets, with the ultimate aim to optimise outcomes and minimise adverse events, such as hypoglycaemia and marked weight gain. The primary goal of the Global Partnership for Effective Diabetes Management is the provision of practical guidance to improve patient outcomes and, in this article, we aim to support healthcare professionals in appropriately tailoring type 2 diabetes treatment to the individual. Patient groups requiring special consideration are identified, including newly diagnosed individuals with type 2 diabetes but no complications, individuals with a history of inadequate glycaemic control, those with a history of cardiovascular disease, children and individuals at risk of hypoglycaemia. Practical guidance specific to each group is provided.

Publication DOI: https://doi.org/10.1111/j.1742-1241.2009.02227.x
Divisions: College of Health & Life Sciences > School of Biosciences
College of Health & Life Sciences > Chronic and Communicable Conditions
College of Health & Life Sciences
Additional Information: © 2010 Blackwell Publishing Ltd Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.
Uncontrolled Keywords: adult,blood glucose,child,type 2 diabetes mellitus,diabetic angiopathies,humans,hypoglycemia,hypoglycemic agents,obesity,overweight,practice guidelines as topic,thinness,General Medicine
Publication ISSN: 1742-1241
Last Modified: 18 Nov 2024 08:06
Date Deposited: 19 Aug 2019 08:53
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
http://onlineli ... 2227.x/abstract (Publisher URL)
PURE Output Type: Article
Published Date: 2010-02
Published Online Date: 2010-01-11
Authors: Del Prato, Stefano
LaSalle, J.
Matthaei, S.
Bailey, Clifford (ORCID Profile 0000-0002-6998-6811)
, Global Partnership for Effective Diabetes Management

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