Diffusing-wave polarimetry for tissue diagnostics

Abstract

We exploit the directional awareness of circularly and/or elliptically polarized light propagating within media which exhibit high numbers of scattering events. By tracking the Stokes vector of the detected light on the Poincaŕe sphere, we demonstrate its applicability for characterization of anisotropy of scattering. A phenomenological model is shown to have an excellent agreement with the experimental data and with the results obtained by the polarization tracking Monte Carlo model, developed in house. By analogy to diffusing-wave spectroscopy we call this approach diffusing-wave polarimetry, and illustrate its utility in probing cancerous and non-cancerous tissue samplesin vitro for diagnostic purposes.

Publication DOI: https://doi.org/10.1117/12.2038658
Divisions: College of Engineering & Physical Sciences > School of Engineering and Technology > Mechanical, Biomedical & Design
College of Engineering & Physical Sciences
Additional Information: Copyright 2014 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Uncontrolled Keywords: Cancer diagnostics,Circular polarization,Helicity,Monte Carlo,Optical biopsy,Poincaré sphere,Polarimetry,Stokes vector,Atomic and Molecular Physics, and Optics,Electronic, Optical and Magnetic Materials,Biomaterials,Radiology Nuclear Medicine and imaging
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.spi ... 12.2038658.full (Publisher URL)
PURE Output Type: Conference article
Published Date: 2014-03-17
Authors: Macdonald, Callum
Doronin, Alexander
Peña, Adrian F.
Eccles, Michael
Meglinski, Igor (ORCID Profile 0000-0002-7613-8191)

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