The influence of local pressure on evaluation parameters of skin blood perfusion and fluorescence

Abstract

This article presents the results of the study of the pressure applied on optical diagnostic probes as a significant factor affecting the results of measurements. During stepwise increasing and decreasing of local pressure on skin we conducted measurements using the methods of laser Doppler flowmetry and fluorescence spectroscopy. It was found out that pressure on optical probe has sufficient impact on skin microcirculation to affect registered fluorescence intensity. Data obtained in this study are of interest for design and development of diagnostic technologies for wearable devices. This data will also inform further investigation into issues of compensation of blood absorption influence on fluorescence spectrum, allowing increased accuracy and reproducibility of measurements by fluorescence spectroscopy methods in optical diagnosis.

Publication DOI: https://doi.org/10.1117/12.2267957
Divisions: College of Engineering & Physical Sciences > School of Engineering and Technology > Mechanical, Biomedical & Design
College of Engineering & Physical Sciences
Additional Information: Copyright 2017 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Uncontrolled Keywords: Blood microcirculation,Fluorescence spectroscopy,Laser Doppler flowmetry,Local pressure,Non-invasive diagnostics,Wearable technology,Electronic, Optical and Magnetic Materials,Atomic and Molecular Physics, and Optics,Biomaterials,Radiology Nuclear Medicine and imaging
Publication ISSN: 1996-756X
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.spi ... 12.2267957.full (Publisher URL)
PURE Output Type: Conference article
Published Date: 2017-03-24
Accepted Date: 2016-09-01
Authors: Zherebtsov, E. A.
Kandurova, K. Y.
Seryogina, E. S.
Kozlov, I. O.
Dremin, V. V.
Zherebtsova, A. I.
Dunaev, A. V.
Meglinski, I. (ORCID Profile 0000-0002-7613-8191)

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