The influence of local pressure on evaluation parameters of skin blood perfusion and fluorescence

Abstract

This article presents the results of the study of the pressure applied on optical diagnostic probes as a significant factor affecting the results of measurements. During stepwise increasing and decreasing of local pressure on skin we conducted measurements using the methods of laser Doppler flowmetry and fluorescence spectroscopy. It was found out that pressure on optical probe has sufficient impact on skin microcirculation to affect registered fluorescence intensity. Data obtained in this study are of interest for design and development of diagnostic technologies for wearable devices. This data will also inform further investigation into issues of compensation of blood absorption influence on fluorescence spectrum, allowing increased accuracy and reproducibility of measurements by fluorescence spectroscopy methods in optical diagnosis.

Publication DOI: https://doi.org/10.1117/12.2267957
Divisions: College of Engineering & Physical Sciences > Aston Institute of Photonics Technology (AIPT)
College of Engineering & Physical Sciences
College of Engineering & Physical Sciences > School of Engineering and Technology > Mechanical, Biomedical & Design
Additional Information: Copyright © 2017 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Event Title: 4th International Symposium on Optics and Biophotonics, SFM 2016
Event Type: Other
Event Dates: 2016-09-27 - 2016-09-30
Uncontrolled Keywords: Blood microcirculation,Fluorescence spectroscopy,Laser Doppler flowmetry,Local pressure,Non-invasive diagnostics,Wearable technology,Electronic, Optical and Magnetic Materials,Atomic and Molecular Physics, and Optics,Biomaterials,Radiology Nuclear Medicine and imaging
Last Modified: 30 Jan 2025 08:25
Date Deposited: 16 Jul 2019 12:09
Full Text Link:
Related URLs: https://www.spi ... 12.2267957.full (Publisher URL)
http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Conference contribution
Published Date: 2017-03-24
Accepted Date: 2016-09-01
Authors: Zherebtsov, E. A.
Kandurova, K. Y.
Seryogina, E. S.
Kozlov, I. O.
Dremin, V. V. (ORCID Profile 0000-0001-6974-3505)
Zherebtsova, A. I.
Dunaev, A. V.
Meglinski, I. (ORCID Profile 0000-0002-7613-8191)

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