Non-invasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles

Abstract

The studies were carried out on groups of clinically healthy mice line of outbred CD-1 stock. The model animals were divided into 2 groups and received experimental liposomal formulations. Using the method of fluorescence spectroscopy, we investigated the effectiveness of penetration into the circulatory system of fluorescently stained liposomes with polyethylene glycol (PEG) and without PEG when administered orally. Fluorescence channel with a fiber probe series of multifunctional laser non-invasive diagnostic system "LAKK-M" (SPE "LAZMA" Ltd, Russia) was used as the measuring equipment.

Publication DOI: https://doi.org/10.1117/12.2269379
Divisions: College of Engineering & Physical Sciences
College of Engineering & Physical Sciences > School of Engineering and Technology > Mechanical, Biomedical & Design
Additional Information: Copyright 2017 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Uncontrolled Keywords: Fluorescence spectroscopy,Fluorescent label,Liposomal nanoparticles,Non-invasive control,Polyethylene glycol,Transport function,Electronic, Optical and Magnetic Materials,Atomic and Molecular Physics, and Optics,Biomaterials,Radiology Nuclear Medicine and imaging
Publication ISSN: 1996-756X
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.spi ... 12.2269379.full (Publisher URL)
PURE Output Type: Conference article
Published Date: 2017-03-24
Accepted Date: 2016-09-01
Authors: Stelmashchuk, O.
Zherebtsov, E.
Zherebtsova, A.
Kuznetsova, E.
Vinokurov, A.
Dunaev, A.
Mamoshin, A.
Snimshchikova, I.
Borsukov, A.
Bykov, A.
Meglinski, I. (ORCID Profile 0000-0002-7613-8191)

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