Influence of probe pressure on diffuse reflectance spectra of human skin measured in vivo

Abstract

Mechanical pressure superficially applied on the human skin surface by a fiber-optic probe influences the spatial distribution of blood within the cutaneous tissues. Upon gradual load of weight on the probe, a stepwise increase in the skin reflectance spectra is observed. The decrease in the load follows the similar inverse staircase-like tendency. The observed stepwise reflectance spectra changes are due to, respectively, sequential extrusion of blood from the topical cutaneous vascular beds and their filling afterward. The obtained results are confirmed by Monte Carlo modeling. This implies that pressure-induced influence during the human skin diffuse reflectance spectra measurements in vivo should be taken into consideration, in particular, in the rapidly developing area of wearable gadgets for real-time monitoring of various human body parameters.

Publication DOI: https://doi.org/10.1117/1.JBO.22.11.110504
Divisions: College of Engineering & Physical Sciences > School of Engineering and Technology > Mechanical, Biomedical & Design
College of Engineering & Physical Sciences
Additional Information: © 2017 SPIE
Uncontrolled Keywords: cutaneous vascular beds,diffuse reflectance spectra,human skin,probe pressure,Electronic, Optical and Magnetic Materials,Biomaterials,Atomic and Molecular Physics, and Optics,Biomedical Engineering
Publication ISSN: 1560-2281
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.spi ... .11.110504.full (Publisher URL)
PURE Output Type: Article
Published Date: 2017-11-20
Accepted Date: 2017-10-27
Authors: Popov, Alexey P.
Bykov, Alexander V.
Meglinski, Igor V. (ORCID Profile 0000-0002-7613-8191)

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