The impact of optical radiation of femtosecond duration on human glial cells

Abstract

The paper presents the results of the studies of influence of optical radiation with wavelengths of 520 and 780 nm on human glial cells (U251) at the range of exposure times ∼ 1-15 min. It was found that after the first minute of irradiation at the wavelength of 780 nm, the relative number of apoptotic cells significantly increased. The result corroborates the concept of biological hazard of optical radiation for tumor cells, and suggests that the approach has a great potential in clinical application for the treatment of human glioma.

Publication DOI: https://doi.org/10.1117/12.2502601
Divisions: College of Engineering & Physical Sciences > School of Engineering and Technology > Mechanical, Biomedical & Design
College of Engineering & Physical Sciences
Additional Information: Copyright 2018 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Uncontrolled Keywords: apoptosis,cell line U251,cytochrome C oxidase,glioma,Irradiation,pulse IR radiation,resonance effect,Electronic, Optical and Magnetic Materials,Condensed Matter Physics,Computer Science Applications,Applied Mathematics,Electrical and Electronic Engineering
Publication ISSN: 1996-756X
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.spi ... 12.2502601.full (Publisher URL)
PURE Output Type: Conference article
Published Date: 2018-10-23
Accepted Date: 2018-10-01
Authors: Ilatovskaia, Diana B.
Porozov, Yuri B.
Demchenko, Petr S.
Meglinski, Igor V. (ORCID Profile 0000-0002-7613-8191)
Khodzitsky, Mikhail K.

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