Speckle dynamics under ergodicity breaking

Abstract

Laser speckle contrast imaging (LSCI) is a well-known and versatile approach for the non-invasive visualization of flows and microcirculation localized in turbid scattering media, including biological tissues. In most conventional implementations of LSCI the ergodic regime is typically assumed valid. However, most composite turbid scattering media, especially biological tissues, are non-ergodic, containing a mixture of dynamic and static centers of light scattering. In the current study, we examined the speckle contrast in different dynamic conditions with the aim of assessing limitations in the quantitative interpretation of speckle contrast images. Based on a simple phenomenological approach, we introduced a coefficient of speckle dynamics to quantitatively assess the ratio of the dynamic part of a scattering medium to the static one. The introduced coefficient allows one to distinguish real changes in motion from the mere appearance of static components in the field of view. As examples of systems with static/dynamic transitions, thawing and heating of Intralipid samples were studied by the LSCI approach.

Publication DOI: https://doi.org/10.1088/1361-6463/aab404
Divisions: College of Engineering & Physical Sciences > School of Engineering and Technology > Mechanical, Biomedical & Design
College of Engineering & Physical Sciences
Uncontrolled Keywords: ergodicity,motion estimation,optical imaging,speckle contrast,speckle pattern,Electronic, Optical and Magnetic Materials,Condensed Matter Physics,Acoustics and Ultrasonics,Surfaces, Coatings and Films
Publication ISSN: 1361-6463
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://iopscie ... 361-6463/aab404 (Publisher URL)
PURE Output Type: Article
Published Date: 2018-03-26
Accepted Date: 2018-03-05
Authors: Sdobnov, Anton
Bykov, Alexander
Molodij, Guillaume
Kalchenko, Vyacheslav
Jarvinen, Topias
Popov, Alexey
Kordas, Krisztian
Meglinski, Igor (ORCID Profile 0000-0002-7613-8191)

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