Impact of physical activity category on incidence of cardiovascular disease:Results from the 10-year follow-up of the ATTICA Study (2002–2012)


The aim of the study was to examine the effects of physical activity (PA) level on 10-year cardiovascular disease (CVD) incidence, taking into consideration several clinical and lifestyle risk factors along with the potential moderating role of gender. An analysis was undertaken on data from the ATTICA prospective cohort study (10-year follow-up, 2002–2012), which followed a Greek adult population (aged 18–89 years). A total n = 317 of fatal and nonfatal CVD events occurred among the 2020 participants. After adjusting for the lifestyle and clinical risk factors as potential confounders, odds ratio (ORs) of CVD risk of individuals who reported being sufficiently active and highly active were decreased by 58% (95% CI: 0.30, 0.58) and 70% (95% CI: 0.15, 0.56), when compared to those who were inactive/insufficiently active, respectively. Men had nearly two-fold increase in risk of CVD (95% CI: 1.62, 2.18) versus women. Stratified analysis by gender, revealed that sufficiently active men, had 52% (95% CI: 0.24, 0.97) reduced risk of CVD incidence when compared to inactive males, while, for women, the role of PA lost significance following adjusting for lifestyle factors. The current data suggests a beneficial effect of even moderate physical activity levels on 10-year incidence of CVD, reinforcing the importance of physically activity, especially for men.

Publication DOI:
Divisions: College of Health & Life Sciences > Aston Medical School
Funding Information: The Hellenic Cardiology Society , the Hellenic Atherosclerosis Society , the Graduate Program in Applied Nutrition and Dietetics of Harokopio University funded this study by research grants (KE252/ELKE/HUA). The ATTICA Study is funded by research grants f
Additional Information: © 2016, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Uncontrolled Keywords: CVD,Physical activity level,Prospective study,Epidemiology,Public Health, Environmental and Occupational Health
Publication ISSN: 1096-0260
Last Modified: 03 Jun 2024 07:40
Date Deposited: 24 Jun 2019 15:03
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.sci ... 281X?via%3Dihub (Publisher URL)
PURE Output Type: Article
Published Date: 2016-12-01
Published Online Date: 2016-09-20
Accepted Date: 2016-09-19
Authors: Tambalis, Konstantinos D.
Panagiotakos, Demosthenes B.
Georgousopoulou, Ekavi N.
Mellor, Duane D. (ORCID Profile 0000-0002-1369-3868)
Chrysohoou, Christina
Kouli, Georgia Maria
Tousoulis, Dimitrios
Stefanadis, Christodoulos
Pitsavos, Christos

Export / Share Citation


Additional statistics for this record