Pilot studies of age-related changes in blood perfusion in two different types of skin


Laser Doppler flowmetry (LDF) was utilized to assess age-related changes in the blood microcirculation at the skin sites with different morphology and regulation. The LDF signals obtained from the glabrous skin of the middle finger pad and nonglabrous skin on the dorsal wrist surface were analyzed. Statistically higher baseline perfusion was observed in the zone with glabrous skin in the older group of volunteers compared to younger participants. Observed site-specific and age-related differences in perfusion can be used in the future experimental design for the studies of the blood microcirculation system in patients with different pathologies.

Publication DOI: https://doi.org/10.1117/12.2522968
Divisions: College of Engineering & Physical Sciences > Aston Institute of Photonics Technology (AIPT)
College of Engineering & Physical Sciences
Additional Information: Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. Funding: Russian Science Foundation (the research project 18-79-00237).
Uncontrolled Keywords: Ageing,Blood microcirculation,Laser Doppler flowmetry,Electronic, Optical and Magnetic Materials,Atomic and Molecular Physics, and Optics,Biomaterials,Radiology Nuclear Medicine and imaging
Publication ISSN: 1996-756X
Last Modified: 23 May 2024 07:14
Date Deposited: 24 Jun 2019 08:21
Full Text Link:
Related URLs: https://www.spi ... 12.2522968.full (Publisher URL)
http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Conference article
Published Date: 2019-06-03
Accepted Date: 2018-09-01
Authors: Loktionova, Yulia
Zharkikh, Elena
Kozlov, Igor
Zherebtsov, Evgeny
Bryanskaya, Svetlana
Zherebtsova, Angelina
Sidorov, Victor
Sokolovski, Sergei (ORCID Profile 0000-0001-7445-7204)
Dunaev, Andrey
Rafailov, Edik (ORCID Profile 0000-0002-4152-0120)
Tuchin, Valery V.



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