The association between sleeping time and metabolic syndrome features among older adults living in Mediterranean region. The MEDIS study.


Background: Metabolic Syndrome (MetS) as a combination of features has been known to significantly increase Cardiovascular Disease (CVD) risk, whilst MetS presence is linked to lifestyle parameters including physical activity and dietary habits; recently, the potential impact of sleeping habits has also become an issue under consideration. The aim of this study was to investigate the role of sleep quantity in several MetS components. Methods: Design:Cross-sectional observational study. Setting: 26 Mediterranean islands and the rural Mani region (Peloponnesus) of Greece. Participants: during 2005-2017, 3130 older (aged 65-100 years) Mediterranean residents were voluntarily enrolled. Measurements: Dietary habits (including MedDietScore assessment), physical activity status, socio-demographic characteristics, lifestyle parameters (sleeping and smoking habits) and clinical profile aspects including Metabolic Syndrome (MetS) components (i.e., waist circumference, systolic and diastolic blood pressure, fasting glucose, triglycerides, LDL and HDL-cholesterol) were derived through standard procedures. Results: The number of daily hours of sleep was independently associated with greater waist circumference (b coefficient per 1 hour=0.91, 95% Confidence Interval (CI); 0.34, 1.49), higher LDL-cholesterol levels (b per 1 hour=3.84, 95%CI; 0.63, 7.05) and lower diastolic blood pressure levels (b per 1 hour=-0.98, 95%CI; - 1.57, -0.39) after adjusting for participants’ age, gender, body mass index, daily walking time, level of adherence to Mediterranean diet and smoking status. No association was revealed between hours of sleep per day and fasting glucose, triglycerides, HDL-cholesterol and systolic blood pressure. Conclusions: Increased hours of sleep is an indicator of metabolic disorders among elderly inviduals, and further research is needed to identify the paths through which sleep quantity is linked to MetS features in different age-groups.

Publication DOI:
Divisions: College of Health & Life Sciences > Aston Medical School
Additional Information: Final publication is available from Mary Ann Liebert, Inc., publishers
Publication ISSN: 1557-8518
Last Modified: 22 Jan 2024 08:27
Date Deposited: 19 Jun 2019 07:56
Full Text Link: https://purepor ... c-syndrome-feat
Related URLs: https://www.lie ... 9/met.2017.0113 (Publisher URL)
PURE Output Type: Article
Published Date: 2018-02-01
Published Online Date: 2018-01-22
Accepted Date: 2018-01-01
Authors: Georgousopoulou, Ekavi
D'Cunha, Nathan
Mellor, Duane (ORCID Profile 0000-0002-1369-3868)
Tyrovolas, Stefanos
Naumovski, Nenad
Foscolou, Alexandra
Bountzioka, Vassoliki
Gotsis, Efthimios
Metallinos, George
Tyrovola, Dimitra
Piscopo, Suzanne
Valacchi, Giuseppe
Tsakountakis, Nikos
Zeimbekis, Akis
Tur, Josep-Antoni
Matalas, Antonia-Leda
Polychronopoulos, Evangelos
Lionis, Chritos
Sidossis, Labros
Panagiotakos, Demosthenes
Group, MEDIS Study



Version: Accepted Version

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