Cocoa and chocolate, their clinical benefits:Insights in study design


Randomized controlled trials and meta-analyses have demonstrated the potential protective effect of cocoa and chocolate consumption with respect to cardiovascular disease (CVD) risk markers. Findings from experimental studies are in concordance with observational data, which include reduction in clinical disease (especially stroke) being associated with chocolate consumption. However, the effect size of any benefit, and the exact mechanism of action due to variability in reporting of dose and type potential bioactive compounds remains unclear. Thus, the present review aimed to analyse the published work where cocoa and chocolate have been assessed for their potential to protect against CVD and highlight the role of study design and type of product used in the variances of outcomes and how that might be used in formulating health advice.

Publication DOI:
Divisions: College of Health & Life Sciences > Aston Medical School
Additional Information: This material has been published in CAB Reviews, Vol 12, Issue 018, 1-7, the only accredited archive of the content that has been certified and accepted after peer review. Copyright and all rights therein are retained by CABl.
Uncontrolled Keywords: Cardiovascular disease,Chocolate,Cocoa,Review,Risk factors,veterinary(all),Agricultural and Biological Sciences(all),Nature and Landscape Conservation
Publication ISSN: 1749-8848
Last Modified: 03 Jun 2024 07:40
Date Deposited: 18 Jun 2019 07:51
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Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Review article
Published Date: 2017-07-03
Accepted Date: 2017-01-01
Authors: Mellor, Duane D. (ORCID Profile 0000-0002-1369-3868)
Georgousopoulou, Ekavi N.
Naumovski, Nenad



Version: Accepted Version

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