IMI – Interventions myopia institute:Interventions for controlling myopia onset and progression report

Abstract

Myopia has been predicted to affect approximately 50% of the world’s population based on trending myopia prevalence figures. Critical to minimizing the associated adverse visual consequences of complicating ocular pathologies are interventions to prevent or delay the onset of myopia, slow its progression, and to address the problem of mechanical instability of highly myopic eyes. Although treatment approaches are growing in number, evidence of treatment efficacy is variable. This article reviews research behind such interventions under four categories: optical, pharmacological, environmental (behavioral), and surgical. In summarizing the evidence of efficacy, results from randomized controlled trials have been given most weight, although such data are very limited for some treatments. The overall conclusion of this review is that there are multiple avenues for intervention worthy of exploration in all categories, although in the case of optical, pharmacological, and behavioral interventions for preventing or slowing progression of myopia, treatment efficacy at an individual level appears quite variable, with no one treatment being 100% effective in all patients. Further research is critical to understanding the factors underlying such variability and underlying mechanisms, to guide recommendations for combined treatments. There is also room for research into novel treatment options.

Publication DOI: https://doi.org/10.1167/iovs.18-25958
Divisions: College of Health & Life Sciences > School of Optometry > Optometry & Vision Science Research Group (OVSRG)
College of Health & Life Sciences
College of Health & Life Sciences > School of Optometry > Vision, Hearing and Language
College of Health & Life Sciences > School of Optometry > Optometry
Additional Information: This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
Uncontrolled Keywords: Behavioral,Myopia control,Optical,Pharmacological,Surgical,Ophthalmology,Sensory Systems,Cellular and Molecular Neuroscience
Publication ISSN: 0146-0404
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://iovs.ar ... ticleid=2727315 (Publisher URL)
PURE Output Type: Article
Published Date: 2019-02-28
Accepted Date: 2018-12-24
Authors: Wildsoet, Christine F.
Chia, Audrey
Cho, Pauline
Guggenheim, Jeremy A.
Polling, Jan Roelof
Read, Scott
Sankaridurg, Padmaja
Saw, Seang Mei
Trier, Klaus
Walline, Jeffrey J.
Wu, Pei Chang
Wolffsohn, James S. (ORCID Profile 0000-0003-4673-8927)

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