Lascar, Nadia, Brown, James, Pattison, Helen, Barnett, Anthony H., Bailey, Clifford J. and Bellary, Srikanth (2018). Type 2 diabetes in adolescents and young adults. The Lancet Diabetes and Endocrinology, 6 (1), pp. 69-80.
Abstract
The prevalence of type 2 diabetes in adolescents and young adults is dramatically increasing. Similar to older-onset type 2 diabetes, the major predisposing risk factors are obesity, family history, and sedentary lifestyle. Onset of diabetes at a younger age (defined here as up to age 40 years) is associated with longer disease exposure and increased risk for chronic complications. Young-onset type 2 diabetes also affects more individuals of working age, accentuating the adverse societal effects of the disease. Furthermore, evidence is accumulating that young-onset type 2 diabetes has a more aggressive disease phenotype, leading to premature development of complications, with adverse effects on quality of life and unfavourable effects on long-term outcomes, raising the possibility of a future public health catastrophe. In this Review, we describe the epidemiology and existing knowledge regarding pathophysiology, risk factors, complications, and management of type 2 diabetes in adolescents and young adults.
Publication DOI: | https://doi.org/10.1016/S2213-8587(17)30186-9 |
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Divisions: | College of Health & Life Sciences > School of Biosciences College of Health & Life Sciences College of Health & Life Sciences > Chronic and Communicable Conditions College of Health & Life Sciences > School of Biosciences > Cell & Tissue Biomedical Research College of Health & Life Sciences > School of Psychology |
Additional Information: | © 2017, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ |
Uncontrolled Keywords: | Diabetes,Type 2,Internal Medicine,Endocrinology, Diabetes and Metabolism,Endocrinology |
Publication ISSN: | 2213-8595 |
Last Modified: | 09 Oct 2024 07:18 |
Date Deposited: | 20 Sep 2017 10:10 |
Full Text Link: | |
Related URLs: |
http://www.scop ... tnerID=8YFLogxK
(Scopus URL) https://www.the ... 0186-9/fulltext (Publisher URL) |
PURE Output Type: | Review article |
Published Date: | 2018-01-01 |
Published Online Date: | 2017-08-25 |
Accepted Date: | 2017-08-08 |
Authors: |
Lascar, Nadia
(
0000-0001-9997-366X)
Brown, James ( 0000-0002-3504-7373) Pattison, Helen ( 0000-0002-9483-4342) Barnett, Anthony H. Bailey, Clifford J. ( 0000-0002-6998-6811) Bellary, Srikanth ( 0000-0002-5924-5278) |
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