Tunable Ag@SiO2 core-shell nanocomposites for broad spectrum antibacterial applications


Silica encapsulated silver nanoparticle core-shell nanocomposites of tunable dimensions were synthesised via a one-pot reverse microemulsion route to achieve controlled release of Ag+ ions for broad spectrum antibacterial application. Silver release rates and bactericidal efficacy against Gram-positive and Gram-negative bacteria, S. aureus and P. aeruginosa respectively, were inversely proportional to nanoparticle core diameter (3-8 nm) and silica shell (7-14 nm) thickness, and readily tuned through a facile hydrothermal etching protocol employing a PVP stabiliser to introduce mesoporosity.

Publication DOI: https://doi.org/10.1039/c7ra03131a
Divisions: College of Engineering & Physical Sciences
College of Health & Life Sciences > School of Biosciences
College of Health & Life Sciences
College of Health & Life Sciences > Chronic and Communicable Conditions
College of Health & Life Sciences > School of Biosciences > Cell & Tissue Biomedical Research
College of Engineering & Physical Sciences > School of Infrastructure and Sustainable Engineering > Chemical Engineering & Applied Chemistry
College of Engineering & Physical Sciences > Energy and Bioproducts Research Institute (EBRI)
Additional Information: This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Uncontrolled Keywords: Chemistry(all),Chemical Engineering(all)
Publication ISSN: 2046-2069
Last Modified: 17 Jun 2024 07:26
Date Deposited: 01 Aug 2017 13:25
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2017-04-27
Accepted Date: 2017-04-20
Submitted Date: 2017-03-16
Authors: Isaacs, Mark A.
Durndell, Lee J.
Hilton, Anthony C. (ORCID Profile 0000-0001-8025-5270)
Olivi, Luca
Parlett, Christopher M.A. (ORCID Profile 0000-0002-3651-7314)
Wilson, Karen (ORCID Profile 0000-0003-4873-708X)
Lee, Adam F.



Version: Published Version

License: Creative Commons Attribution

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