Laughton, Deborah S., Sheppard, Amy L. and Davies, Leon N. (2018). Refraction during incipient presbyopia:the Aston Longitudinal Assessment of Presbyopia (ALAP) study. Journal of Optometry, 11 (1), pp. 49-56.
Abstract
Purpose: To investigate non-cycloplegic changes in refractive error prior to the onset of presbyopia. Methods: The Aston Longitudinal Assessment of Presbyopia (ALAP) study is a prospective 2.5 year longitudinal study, measuring objective refractive error using a binocular open-field WAM-5500 autorefractor at 6-month intervals in participants aged between 33 and 45 years. Results: From the 58 participants recruited, 51 participants (88%) completed the final visit. At baseline, 21 participants were myopic (MSE -3.25 ± 2.28 DS; baseline age 38.6 ± 3.1 years) and 30 were emmetropic (MSE −0.17 ± 0.32 DS; baseline age 39.0 ± 2.9 years). After 2.5 years, 10% of the myopic group experienced a hypermetropic shift (≥0.50 D), 5% a myopic shift (≥0.50 D) and 85% had no significant change in refraction (<0.50 D). From the emmetropic group, 10% experienced a hypermetropic shift (≥0.50 D), 3% a myopic shift (≥0.50 D) and 87% had no significant change in refraction (<0.50 D). In terms of astigmatism vectors, other than J45 (p < 0.001), all measures remained invariant over the study period. Conclusion: The incidence of a myopic shift in refraction during incipient presbyopia does not appear to be as large as previously indicated by retrospective research. The changes in axis indicate ocular astigmatism tends towards the against-the-rule direction with age. The structural origin(s) of the reported myopic shift in refraction during incipient presbyopia warrants further investigation.
Publication DOI: | https://doi.org/10.1016/j.optom.2017.02.001 |
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Divisions: | College of Health & Life Sciences College of Health & Life Sciences > School of Optometry > Optometry College of Health & Life Sciences > School of Optometry > Optometry & Vision Science Research Group (OVSRG) College of Health & Life Sciences > School of Optometry > Vision, Hearing and Language |
Additional Information: | © 2017, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ |
Uncontrolled Keywords: | presbyopia,myopia,refractive error,Optometry |
Publication ISSN: | 1989-1342 |
Last Modified: | 02 Oct 2024 07:16 |
Date Deposited: | 07 Mar 2017 13:55 |
Full Text Link: | |
Related URLs: |
http://www.scop ... tnerID=8YFLogxK
(Scopus URL) |
PURE Output Type: | Article |
Published Date: | 2018-01 |
Published Online Date: | 2017-06-07 |
Accepted Date: | 2017-02-24 |
Submitted Date: | 2016-09-22 |
Authors: |
Laughton, Deborah S.
Sheppard, Amy L. ( 0000-0003-0035-8267) Davies, Leon N. ( 0000-0002-1554-0566) |
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