PCOS remains a diagnosis of exclusion:a concise review of key endocrinopathies to exclude


Polycystic ovarian syndrome (PCOS) is a heterogenous disorder associated with clinical, endocrine and ultrasonographic features that can also be encountered in a number of other diseases. It has traditionally been suggested that prolactin excess, enzymatic steroidogenic abnormalities and thyroid disorders need to be excluded before a diagnosis of PCOS is made. However, there is paucity of data regarding the prevalence of PCOS phenotype in some of these disorders, whereas other endocrine diseases that exhibit PCOS-like features may elude diagnosis and proper management if not considered. This article reviews the data of currently included entities that exhibit a PCOS phenotype and those that potentially need to be looked for, and attempts to identify specific features that distinguish them from idiopathic PCOS.

Publication DOI: https://doi.org/10.1111/cen.13245
Divisions: College of Health & Life Sciences > Aston Medical School
Additional Information: This is the peer reviewed version of the following article: Kyritsi, E. M., Dimitriadis, G. K., Kyrou, I., Kaltsas, G., & Randeva, H. S. (2017). PCOS remains a diagnosis of exclusion: a concise review of key endocrinopathies to exclude. Clinical Endocrinology, 86 (1) 1-6, which has been published in final form at http://dx.doi.org/10.1111/cen.13245. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Uncontrolled Keywords: Endocrinology, Diabetes and Metabolism
Publication ISSN: 1365-2265
Last Modified: 14 Jun 2024 07:14
Date Deposited: 06 Dec 2016 14:25
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Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Review article
Published Date: 2017-01-01
Published Online Date: 2016-10-11
Accepted Date: 2016-09-15
Authors: Kyritsi, Eleni Magdalini
Dimitriadis, George K.
Kyrou, Ioannis (ORCID Profile 0000-0002-6997-3439)
Kaltsas, Gregory
Randeva, Harpal S.



Version: Accepted Version

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