Towards novel compact laser sources for non-invasive diagnostics and treatment

Abstract

An important field of application of lasers is biomedical optics. Here, they offer great utility for diagnosis, therapy and surgery. For the development of novel methods of laser-based biomedical diagnostics careful study of light propagation in biological tissues is necessary to enhance our understanding of the optical measurements undertaken, increase research and development capacity and the diagnostic reliability of optical technologies. Ultimately, fulfilling these requirements will increase uptake in clinical applications of laser based diagnostics and therapeutics. To address these challenges informative biomarkers relevant to the biological and physiological function or disease state of the organism must be selected. These indicators are the results of the analysis of tissues and cells, such as blood. For non-invasive diagnostics peripheral blood, cells and tissue can potentially provide comprehensive information on the condition of the human organism. A detailed study of the light scattering and absorption characteristics can quickly detect physiological and morphological changes in the cells due to thermal, chemical, antibiotic treatments, etc [1-5]. The selection of a laser source to study the structure of biological particles also benefits from the fact that gross pathological changes are not induced and diagnostics make effective use of the monochromatic directional coherence properties of laser radiation.

Publication DOI: https://doi.org/10.1117/12.2193777
Divisions: College of Engineering & Physical Sciences > Aston Institute of Photonics Technology (AIPT)
College of Engineering & Physical Sciences
Additional Information: Edik U. Rafailov ; Karina S. Litvinova and Sergei G. Sokolovski, "Towards novel compact laser sources for non-invasive diagnostics and treatment", Proc. SPIE 9550, Biosensing and Nanomedicine VIII, 95500G (August 21, 2015) Copyright 2015. Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. DOI: http://dx.doi.org/10.1117/12.2193777
Event Title: Biosensing and nanomedicine VIII
Event Type: Other
Event Dates: 2015-08-09 - 2015-08-12
Uncontrolled Keywords: Applied Mathematics,Computer Science Applications,Electrical and Electronic Engineering,Electronic, Optical and Magnetic Materials,Condensed Matter Physics
ISBN: 9781628417166
Last Modified: 03 Oct 2024 07:08
Date Deposited: 28 Jan 2016 09:55
Full Text Link: http://proceedi ... ticleid=2430914
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Conference contribution
Published Date: 2015-08-21
Authors: Rafailov, Edik U. (ORCID Profile 0000-0002-4152-0120)
Litvinova, Karina S. (ORCID Profile 0000-0003-1110-8589)
Sokolovski, Sergei G. (ORCID Profile 0000-0001-7445-7204)

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