Clinical guidelines on long-term pharmacotherapy for bipolar disorder in children and adolescents


Bipolar disorder is a severe affective disorder which can present in adolescence, or sometimes earlier, and often requires a pharmacotherapeutic approach. The phenomenology of bipolar disorder in children and adolescents appears to differ from that of adult patients, prompting the need for specific pharmacotherapy guidelines for long-term management in this patient population. Current treatment guidelines were mainly developed based on evidence from studies in adult patients, highlighting the requirement for further research into the pharmacotherapy of children and adolescents with bipolar disorder. This review compares and critically analyzes the available guidelines, discussing the recommended medication classes, their mechanisms of action, side effect profiles and evidence base

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Divisions: College of Health & Life Sciences > School of Psychology
College of Health & Life Sciences > Clinical and Systems Neuroscience
College of Health & Life Sciences > Aston Institute of Health & Neurodevelopment (AIHN)
College of Health & Life Sciences
Additional Information: © 2014 by the authors; licensee MDPI, Basel, Switzerland. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Uncontrolled Keywords: adolescents,bipolar disorder ,children,guidelines,pharmacotherapy
Publication ISSN: 1550-9397
Last Modified: 22 Feb 2024 08:09
Date Deposited: 15 Oct 2015 13:45
Full Text Link: http://www.mdpi ... 77-0383/3/1/135
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PURE Output Type: Review article
Published Date: 2014-01-21
Authors: Cox, Joanna H.
Seri, Stefano (ORCID Profile 0000-0002-9247-8102)
Cavanna, Andrea E.



Version: Published Version

License: Creative Commons Attribution

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