Dunbar, Lynsey, Sowden, Rebecca J., Trotter, Katherine D., Taylor, Michelle K., Smith, David, Kennedy, Alan R., Reglinski, John and Spickett, Corinne M. (2015). Copper complexes as a source of redox active MRI contrast agents. BioMetals, 28 (5), pp. 903-912.
Abstract
The study reports an advance in designing copper-based redox sensing MRI contrast agents. Although the data demonstrate that copper(II) complexes are not able to compete with lanthanoids species in terms of contrast, the redox-dependent switch between diamagnetic copper(I) and paramagnetic copper(II) yields a novel redox-sensitive contrast moiety with potential for reversibility.
| Publication DOI: | https://doi.org/10.1007/s10534-015-9875-3 |
|---|---|
| Divisions: | College of Health & Life Sciences > School of Biosciences College of Health & Life Sciences College of Health & Life Sciences > Chronic and Communicable Conditions Aston University (General) |
| Additional Information: | The final publication is available at Springer via http://dx.doi.org/10.1007/s10534-015-9875-3 Funding: BBSRC (BBS/B/01553). Electronic supplementary material (doi: 10.1007/s10534-015-9875-3). |
| Uncontrolled Keywords: | copper macrocycles,oxidation–reduction,Redox sensitive contrast agent,imaging,inflammation,Biomaterials,Metals and Alloys,General Agricultural and Biological Sciences,General Biochemistry,Genetics and Molecular Biology |
| Publication ISSN: | 1572-8773 |
| Last Modified: | 05 Nov 2024 08:13 |
| Date Deposited: | 19 Aug 2015 11:20 |
| Full Text Link: |
http://link.spr ... 0534-015-9875-3 |
| Related URLs: |
http://www.scop ... tnerID=8YFLogxK
(Scopus URL) |
PURE Output Type: | Article |
| Published Date: | 2015 |
| Published Online Date: | 2015-08-09 |
| Authors: |
Dunbar, Lynsey
Sowden, Rebecca J. Trotter, Katherine D. Taylor, Michelle K. Smith, David Kennedy, Alan R. Reglinski, John Spickett, Corinne M. ( 
0000-0003-4054-9279)
|
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