Innervation of the rat oesophagus

Abstract

The response of the isolated rat oesophagus to electrical stimulation and the effect of drugs and variations in both stimulation frequency and temperature on these responses were studied. Responses were recorded from the circular and longitudinal oesophageal muscles and the cardia. Both circular and longitudinal responses consisted of twitch and sustained components, the latter having an additional slow component. The twitch was decreased by shortening the interval between volleys; preceding each volley with a single stimulus or increasing the intralumenal volume. It is proposed that the relaxation phase of the twitch is due to mechanical changes in the muscularis externa and that it is 'fast' striated muscle...

Publication DOI: https://doi.org/10.48780/publications.aston.ac.uk.00021935
Divisions: College of Health & Life Sciences > Aston Pharmacy School
Additional Information: Copyright © DEREK ARTHUR WESTWOOD, 1976. DEREK ARTHUR WESTWOOD asserts their moral right to be identified as the author of this thesis. This copy of the thesis has been supplied on condition that anyone who consults it is understood to recognise that its copyright rests with its author and that no quotation from the thesis and no information derived from it may be published without appropriate permission or acknowledgement. If you have discovered material in Aston Publications Explorer which is unlawful e.g. breaches copyright, (either yours or that of a third party) or any other law, including but not limited to those relating to patent, trademark, confidentiality, data protection, obscenity, defamation, libel, then please read our Takedown Policy and contact the service immediately.
Institution: Aston University
Last Modified: 20 Feb 2025 14:06
Date Deposited: 27 Mar 2014 15:00
Completed Date: 1976-09
Authors: Westwood, Derek Arthur

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