Statistical guidelines for clinical studies of human vision


Citation information: Armstrong RA, Davies LN, Dunne MCM & Gilmartin B. Statistical guidelines for clinical studies of human vision. Ophthalmic Physiol Opt 2011, 31, 123-136. doi: 10.1111/j.1475-1313.2010.00815.x ABSTRACT: Statistical analysis of data can be complex and different statisticians may disagree as to the correct approach leading to conflict between authors, editors, and reviewers. The objective of this article is to provide some statistical advice for contributors to optometric and ophthalmic journals, to provide advice specifically relevant to clinical studies of human vision, and to recommend statistical analyses that could be used in a variety of circumstances. In submitting an article, in which quantitative data are reported, authors should describe clearly the statistical procedures that they have used and to justify each stage of the analysis. This is especially important if more complex or 'non-standard' analyses have been carried out. The article begins with some general comments relating to data analysis concerning sample size and 'power', hypothesis testing, parametric and non-parametric variables, 'bootstrap methods', one and two-tail testing, and the Bonferroni correction. More specific advice is then given with reference to particular statistical procedures that can be used on a variety of types of data. Where relevant, examples of correct statistical practice are given with reference to recently published articles in the optometric and ophthalmic literature.

Publication DOI:
Divisions: College of Health & Life Sciences > School of Optometry > Optometry
College of Health & Life Sciences > School of Optometry > Optometry & Vision Science Research Group (OVSRG)
College of Health & Life Sciences
College of Health & Life Sciences > School of Optometry > Vision, Hearing and Language
College of Health & Life Sciences > Clinical and Systems Neuroscience
Additional Information: © 2011 The College of Optometrists. Backwell publishing. The definitive version is available at
Uncontrolled Keywords: analysis of variance,clinical studies,data analysis,human vision,statistical guidelines,Ophthalmology,Optometry,Sensory Systems
Publication ISSN: 1475-1313
Last Modified: 05 Jun 2024 07:09
Date Deposited: 02 Mar 2011 11:47
Full Text Link: http://onlineli ... 0815.x/abstract
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2011-03
Authors: Armstrong, Richard A. (ORCID Profile 0000-0002-5046-3199)
Davies, Leon N. (ORCID Profile 0000-0002-1554-0566)
Dunne, Mark C.M. (ORCID Profile 0000-0001-9126-0702)
Gilmartin, Bernard



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