Some of the Corneal Effects Produced by Wearing Hydrogel Contact Lenses Soaked in a Non-Isotonic Saline

Abstract

The corneal response to daily and extended wear hydrogel contact lenses was evaluated when the lenses were soaked in non-isotonic solutions varying from 0.7 to 1.2 percent. The naturally occuring diurnal variations of the cornea were examined to discover what effect they may have on contact lens wear. It was noted that there were significant corneal hydration changes. Initially there was swelling of the cornea which subsided after four hours. There were no changes in the central anterior radius of the cornea. No realtionship could be found between intraocular pressure and corneal hydration in different Ves. It appears that intraocular pressure is an independent parameter...