Aitchison, Eileen J. (1987). The Antigenic Composition of Streptococcus Faecalis Associated with Ineffective Endocarditis. PHD thesis, Aston University.
Abstract
The composition of the cell wall of Streptococcus faecalis was examined for the presence of specialised structures or components responsible for attachment to host endocardial tissue in infective endocarditis (IE). Analysis of cells by sodium dodecylsulphate-polyacrylamide gel electrophoresis (SDS-PAGE), crossed immunoelectrophoresis (CIE) and immunoblotting revealed that the protein and antigenic profiles of cells grown in complex laboratory medium were different to those of cells grown in conditions approximating to the in vivo environment. The antigenic pattern of S. faecalis was more complex after growth in brain-heart infusion than after growth in serum. Growth in serum resulted in expression of three major protein antigens, 73, 40 and 37K, which were characteristic of S. faecalis species and were absent from other streptococcal species and Staphylococcus aureus...
| Publication DOI: | https://doi.org/10.48780/publications.aston.ac.uk.00012558 |
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| Divisions: | College of Health & Life Sciences |
| Additional Information: | Copyright © Eileen J. Aitchison, 1987 Eileen J. Aitchison asserts their moral right to be identified as the author of this thesis. This copy of the thesis has been supplied on condition that anyone who consults it is understood to recognise that its copyright rests with its author and that no quotation from the thesis and no information derived from it may be published without appropriate permission or acknowledgement. If you have discovered material in Aston Publications Explorer which is unlawful e.g. breaches copyright, (either yours or that of a third party) or any other law, including but not limited to those relating to patent, trademark, confidentiality, data protection, obscenity, defamation, libel, then please read our Takedown Policy and contact the service immediately. |
| Institution: | Aston University |
| Uncontrolled Keywords: | antigenic composition,Streptococcus faecalis,ineffective endocarditis |
| Last Modified: | 01 Apr 2025 11:16 |
| Date Deposited: | 24 Jan 2011 11:29 |
| Completed Date: | 1987-09 |
| Authors: |
Aitchison, Eileen J.
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