Hamon, Christopher G.B. (1984). Tetrahydrobiopterin metabolism. PHD thesis, Aston University.
Abstract
A technique for the measurement of biopterin using HPLC has been developed and compared against the established Crithidia fasciculata assay. The two assays give a similar reading when samples are unoxidised but after acid/iodine oxidation Crithidia reads higher, probably due to the presence of other pterins. Using HPLC as a measuring technique an oral dose of phenylalanine has been found to elevate the level of biopterin derivatives in the blood whilst tyrosine had no effect...
| Publication DOI: | https://doi.org/10.48780/publications.aston.ac.uk.00011757 |
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| Divisions: | College of Engineering & Physical Sciences > School of Infrastructure and Sustainable Engineering > Chemical Engineering & Applied Chemistry |
| Additional Information: | Copyright © C.G.B. Hamon, 1984. C.G.B. Hamon asserts their moral right to be identified as the author of this thesis. This copy of the thesis has been supplied on condition that anyone who consults it is understood to recognise that its copyright rests with its author and that no quotation from the thesis and no information derived from it may be published without appropriate permission or acknowledgement. If you have discovered material in Aston Publications Explorer which is unlawful e.g. breaches copyright, (either yours or that of a third party) or any other law, including but not limited to those relating to patent, trademark, confidentiality, data protection, obscenity, defamation, libel, then please read our Takedown Policy and contact the service immediately. |
| Institution: | Aston University |
| Uncontrolled Keywords: | tetrahydrobiopterin metabolism,HPLC,Brain,Neurotransmitter,Senile Dementia |
| Last Modified: | 21 Mar 2025 10:30 |
| Date Deposited: | 13 Jan 2011 11:50 |
| Completed Date: | 1984 |
| Authors: |
Hamon, Christopher G.B.
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