Ocular Compatibility of Hydrogels

Abstract

The primary objective of this research was to investigate the effects of long term wear on the ocular compatibility of hydrogel contact lenses with reference to the incidence of deposits. A number of spoilt lenses, representative of a wide range of lens chemistries were examined. A variety of analytical and histological techniques were developed in order to characterise the morphology, chemical composition and geology of lens deposits. Four major manifestations of hydrogel spoilation, discrete elevated deposits, lens discolouration, and lens surface coatings and plaques were examined...