Stimulus-Mitosis Coupling in the Rat Thymic Lymphocyte

Abstract

Quiescent thymocytes are stimulated to divide by a variety of compounds. These may be subdivided into four categories. The first group includes parathyroid hormone, vitamin D3 and its metabolites and raised extracellular calcium concentrations. Enhanced calcium influx provoked directly or possibly via cGMP production is the prelude to calmodulin activation which subsequently triggers cell arousal by a process which is independent of magnesium ions. High oestradiol concentrations by further increasing intra— cellular calcium concentrations beyond a threshold inhibit this response...

Publication DOI: https://doi.org/10.48780/publications.aston.ac.uk.00010554
Divisions: College of Health & Life Sciences > School of Biosciences
Additional Information: Copyright © Christina Cade, 1983. Christina Cade asserts their moral right to be identified as the author of this thesis. This copy of the thesis has been supplied on condition that anyone who consults it is understood to recognise that its copyright rests with its author and that no quotation from the thesis and no information derived from it may be published without appropriate permission or acknowledgement. If you have discovered material in Aston Publications Explorer which is unlawful e.g. breaches copyright, (either yours or that of a third party) or any other law, including but not limited to those relating to patent, trademark, confidentiality, data protection, obscenity, defamation, libel, then please read our Takedown Policy and contact the service immediately.
Institution: Aston University
Uncontrolled Keywords: Stimulus-mitosis coupling,rat,thymic lymphocyte
Last Modified: 20 Mar 2025 09:51
Date Deposited: 10 Jan 2011 13:45
Completed Date: 1983
Authors: Cade, Christina

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