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Number of items: 49.

Article

Wang, Zhuo, Stuckey, Daniel J., Murdoch, Colin E., Camelliti, Patrizia, Lip, Gregory Y.H. and Griffin, Martin (2018). Cardiac fibrosis can be attenuated by blocking the activity of transglutaminase 2 using a selective small-molecule inhibitor. Cell Death and Disease, 9 ,

Ayinde, Oluseyi, Wang, Zhuo and Griffin, Martin (2017). Tissue transglutaminase induces epithelial-mesenchymal-transition and the acquisition of stem cell like characteristics in colorectal cancer cells. Oncotarget, 8 (12), pp. 20025-20041.

Zonca, Sara, Pinton, Giulia, Wang, Zhuo, Soluri, Maria Felicia, Tavian, Daniela, Griffin, Martin, Sblattero, Daniele and Moro, Laura (2017). Tissue transglutaminase (TG2) enables survival of human malignant pleural mesothelioma cells in hypoxia. Cell Death and Disease, 8 (2),

Feriotto, G., Calza, R., Bergamini, C.M., Griffin, M., Wang, Z., Beninati, S., Ferretti, V., Marzola, E., Guerrini, R., Pagnoni, A., Cavazzini, A., Casciano, F. and Mischiati, C. (2016). Involvement of cell surface TG2 in the aggregation of K562 cells triggered by gluten. Amino Acids, In pre ,

Nyabam, Samuel, Wang, Zhuo, Thibault, Thomas, Ayinde, Oluseyi, Basar, Rameeza, Marshall, Lindsay and Griffin, Martin (2016). A novel regulatory role for tissue transglutaminase in epithelial-mesenchymal transition in cystic fibrosis. BBA - Molecular Cell Research, 1863 (9), pp. 2234-2244.

Kiraly, Robert, Thangaraju,, Kiruphagaran, Nagy, Zsófia, Collighan, Russell, Nemes, Zoltán, Griffin, Martin and Fésüs, László (2016). Isopeptidase activity of human transglutaminase 2:disconnection from transamidation and characterization by kinetic parameters. Amino Acids, 48 (1), pp. 31-40.

Badarau, Eduard, Wang, Zhuo, Rathbone, Dan L., Costanzi, Andrea, Thibault, Thomas, Murdoch, Colin E., El Alaoui, Said, Bartkeviciute, Milda and Griffin, Martin (2015). Development of potent and selective tissue transglutaminase inhibitors:their effect on TG2 function and application in pathological conditions. Chemistry and Biology, 22 (10), pp. 1347-1361.

Nadella, Vinod, Wang, Zhuo, Johnson, Timothy S., Griffin, Martin and Devitt, Andrew (2015). Transglutaminase 2 interacts with syndecan-4 and CD44 at the surface of human macrophages to promote removal of apoptotic cells. BBA - Molecular Cell Research, 1853 (1), pp. 201-212.

Nadalutti, Cristina A., Korponay-Szabo, Ilma R., Kaukinen, Katri, Wang, Zhuo, Griffin, Martin, Mäki, Markku and Lindfors, Katri (2013). Thioredoxin is involved in endothelial cell extracellular transglutaminase 2 activation mediated by celiac disease patient IgA. PLoS ONE, 8 (10),

Kalliokoski, Suvi, Sulic, Ana-Marija, Korponay-Szabó, Ilma R., Szondy, Zsuzsa, Frias, Rafael, Perez, Mileidys A., Martucciello, Stefania, Roivainen, Anne, Pelliniemi, Lauri J., Esposito, Carla, Griffin, Martin, Sblattero, Daniele, Mäki, Markku, Kaukinen, Katri, Lindfors, Katri and Caja, Sergio (2013). Celiac disease-specific TG2-targeted autoantibodies inhibit angiogenesis ex vivo and in vivo in mice by interfering with endothelial cell dynamics. PLoS ONE, 8 (6),

Wang, Zhuo and Griffin, Martin (2013). The role of TG2 in regulating S100A4-mediated mammary tumour cell migration. PLoS ONE, 8 (3),

Badarau, Eduard, Collighan, Russell J. and Griffin, Martin (2013). Recent advances in the development of tissue transglutaminase (TG2) inhibitors. Amino Acids, 44 (1), pp. 119-127.

Wang, Z., Perez, M., Caja, S., Melino, G., Johnson, T.S., Lindfors, K. and Griffin, M. (2013). A novel extracellular role for tissue transglutaminase in matrix-bound VEGF-mediated angiogenesis. Cell Death and Disease, 4 (9),

Wang, Zhuo, Collighan, Russell, Pytel, Kamila, Rathbone, Dan L, Li, Xiaoling and Griffin, Martin (2012). Characterization of heparin-binding site of tissue transglutaminase:its importance in cell surface targeting, matrix deposition, and cell signaling. Journal of Biological Chemistry, 287 (16), pp. 13063-13083.

Kotsakis, Panayiotis, Wang, Zhuo, Collighan, Russell John and Griffin, Martin (2011). The role of tissue transglutaminase (TG2) in regulating the tumour progression of the mouse colon carcinoma CT26. Amino Acids, 41 (4), pp. 909-921.

Sarang, Zsolt, Köröskényi, Krisztina, Pallai, Anna, Duró, Edina, Melino, Gerry, Griffin, Martin, Fésüs, László and Szondy, Zsuzsa (2011). Transglutaminase 2 null macrophages respond to lipopolysaccharide stimulation by elevated proinflammatory cytokine production due to an enhanced αvβ3 integrin-induced Src tyrosine kinase signaling. Immunology Letters, 138 (1), pp. 71-78.

Rauhavirta, T., Qiao, S.-W., Jiang, Z., Myrsky, E., Loponen, J., Korponay-Szabó, I.R., Salovaara, H., Garcia-Horsman, J.A., Venäläinen, J., Männistö, P.T., Collighan, R., Mongeot, A., Griffin, M., Mäki, M., Kaukinen, K. and Lindfors, K. (2011). Epithelial transport and deamidation of gliadin peptides:a role for coeliac disease patient immunoglobulin A. Clinical and Experimental Immunology, 164 (1), pp. 127-136.

Wang, Zhuo, Collighan, Russell J, Gross, Stephane R, Danen, Erik H. J., Orend, Gertraud, Telci, Dilek and Griffin, Martin (2010). RGD-independent cell adhesion via a tissue transglutaminase-fibronectin matrix promotes fibronectin fibril deposition and requires syndecan-4/2 and α5β1 integrin co-signaling. Journal of Biological Chemistry, 285 (51), pp. 40212-40129.

Mutch, N.J., Koikkalainen, J.S., Fraser, S.R., Duthie, K.M., Griffin, Martin, Mitchell, J., Watson, H.G. and Booth, N.A. (2010). Model thrombi formed under flow reveal the role of factor XIII-mediated cross-linking in resistance to fibrinolysis. Journal of Thrombosis and Haemostasis, 8 (9), pp. 2017-2024.

Chau, David Y.S., Tint, Naing L., Collighan, Russell J, Griffin, Martin, Dua, Harminder S., Shakesheff, Kevin M. and Rose, Felicity R.A.J. (2010). The visualisation of vitreous using surface modified poly(lactic-co-glycolic acid) microparticles. British Journal of Ophthalmology, 94 (5), pp. 648-653.

Telci, Dilek, Collighan, Russell, Basaga, Huveyda and Griffin, Martin (2009). Increased TG2 expression can result in induction of transforming growth factor β1, causing increased synthesis and deposition of matrix proteins, which can be regulated by nitric oxide. Journal of Biological Chemistry, 284 (43), pp. 29547-29558.

Huang, Linghong, Haylor, John L., Hau, Zoe, Jones, Richard A., Vickers, Melissa E., Wagner, Bart, Griffin, Martin, Saint, Robert E., Coutts, Ian G.C., El Nahas, A. Meguid and Johnson, Timothy S. (2009). Transglutaminase inhibition ameliorates experimental diabetic nephropathy. Kidney international, 76 (4), pp. 383-394.

Telci, Dilek, Wang, Zhuo, Li, Xiaoling, Verderio, Elisabetta A.M., Humphries, Martin J., Baccarini, Manuela, Basaga, Huveyda and Griffin, Martin (2008). Fibronectin-tissue transglutaminase matrix rescues RGD-impaired celladhesion through syndecan-4 and β integrin co-signaling. Journal of Biological Chemistry, 283 (30), pp. 20937-20947.

Beck, Katy E., De Girolamo, Luigi A., Griffin, Martin and Billett, E. Ellen (2006). The role of tissue transglutaminase in 1-methyl-4-phenylpyridinium (MPP+)-induced toxicity in differentiated human SH-SY5Y neuroblastoma cells. Neuroscience Letters, 405 (1-2), pp. 46-51.

Skill, Nicholas J., Johnson, Timothy S., Coutts, Ian G .C., Saint, Robert E., Fisher, Marie, Huang, Linghong, El Nahas, A. Meguid, Collighan, Russell and Griffin, Martin (2004). Inhibition of transglutaminase activity reduces extracellular matrix accumulation induced by high glucose levels in proximal tubular epithelial cells. Journal of Biological Chemistry, 279 (46), pp. 47754-47762.

Trigwell, Susan M., Lynch, Paul T., Griffin, Martin, Hargreaves, Alan J. and Bonner, Philip L.R. (2004). An improved colorimetric assay for the measurement of transglutaminase (type II) ε-(γ-glutamyl) lysine cross-linking activity. Analytical Biochemistry, 330 (1), pp. 164-166.

El Nahas, A.M., Abo-Zenah, H., Skill, N.J., Bex, S., Wild, G., Griffin, M. and Johnson, T.S. (2004). Elevated ε-(γ-glutamyl)lysine in human diabetic nephropathy results from increased expression and cellular release of tissue transglutaminase. Nephron Clinical Practice, 97 (3), pp. 108-117.

Baumgartner, Werner, Golenhofen, Nikola, Weth, Agnes, Hiiragi, Takashi, Saint, Rob, Griffin, Martin and Drenckhahn, Detlev (2004). Role of transglutaminase 1 in stabilisation of intercellular junctions of the vascular endothelium. Histochemistry and Cell Biology, 122 (1), pp. 17-25.

Collighan, Russell, Clara, Santiago, Li, Xiaoling, Parry, James and Griffin, Martin (2004). Transglutaminases as tanning agents for the leather industry. Journal of the American Leather Chemists Association, 99 (7), pp. 293-302.

Johnson, Timothy S., Abo-Zenah, Hamdy, Skill, James N., Bex, Samantha, Wild, Graham, Brown, Colin B., Griffin, Martin and El Nahas, A. Meguid (2004). Tissue transglutaminase:a mediator and predictor of chronic allograft nephropathy? Transplantation, 77 (11), pp. 1667-1675.

Verderio, Elisabetta A.M., Telci, Dilek, Okoye, Afam, Melino, Gerry and Griffin, Martin (2003). A novel RGD-independent cel adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikis. Journal of Biological Chemistry, 278 (43), pp. 42604-42614.

Johnson, Timothy S., El-Koraie, Ahmed F., Skill, N. James, Baddour, Nahed M., El Nahas, A. Meguid., Njloma, Melvin, Adam, Ahmed G. and Griffin, Martin (2003). Tissue transglutaminase and the progression of human renal scarring. Journal of the American Society of Nephrology, 14 (8), pp. 2052-2062.

Gross, Stephane R., Balklava, Zita and Griffin, Martin (2003). Importance of tissue transglutaminase in repair of extracellular matrices and cell death of dermal fibroblasts after exposure to a solarium ultraviolet A source. Journal of Investigative Dermatology, 121 (2), pp. 412-423.

Nicholas, Ben, Smethurst, Peter, Verderio, Elisabetta, Jones, Richard and Griffin, Martin (2003). Cross-linking of cellular proteins by tissue transglutaminase during necrotic cell death:a mechanism for maintaining tissue integrity. Biochemical Journal, 371 (2), pp. 413-422.

Senior, Karl, Griffin, Martin and Collighan, Russell (2003). Novel approach to improving enzyme penetration. British Leather Technology Centre journal, 46 ,

Collighan, Russell and Griffin, Martin (2003). Transglutaminases in the leather industry. British Leather Technology Centre journal, 46 ,

Griffin, Martin, Casadio, Rita and Bergamini, Carlo M. (2002). Transglutaminases:nature's biological glues. Biochemical Journal, 368 (Pt 2), pp. 377-396.

Piacentini, Mauro, Farrace, Maria Grazia, Piredda, Lucia, Matarrese, Paola, Ciccosanti, Fabiola, Falasca, Laura, Rodolfo, Carlo, Giammarioli, Anna Maria, Verderio, Elisabetta, Griffin, Martin and Malorni, Walter (2002). Transglutaminase overexpression sensitizes neuronal cell lines to apoptosis by increasing mitochondrial membrane potential and cellular oxidative stress. Journal of Neurochemistry, 81 (5), pp. 1061-1072.

Collighan, Russell, Cortez, João and Griffin, Martin (2002). The biotechnological applications of transglutaminases. Minerva Biotecnologica, 14 (2), pp. 143-148.

Coombes, A.G.A., Verderio, E., Shaw, B., Li, Xiaoling, Griffin, Martin and Downes, S. (2002). Biocomposites of non-crosslinked natural and synthetic polymers. Biomaterials, 23 (10), pp. 2113-2118.

Heath, Deborah J., Christian, Paul and Griffin, Martin (2002). Involvement of tissue transglutaminase in the stabilisation of biomaterial/tissue interfaces important in medical devices. Biomaterials, 23 (6), pp. 1519-1526.

Balklava, Zita, Verderio, Elisabetta, Collighan, Russell, Gross, Stephane, Adams, Julian and Griffin, Martin (2002). Analysis of tissue transglutaminase function in the migration of Swiss 3T3 fibroblasts:the active-state conformation of the enzyme does not affect cell motility but is important for its secretion. Journal of Biological Chemistry, 277 (19), pp. 16567-16575.

Heath, Deborah J., Downes, Sandra, Verderio, Elisabetta and Griffin, Martin (2001). Characterization of tissue transglutaminase in human osteoblast-like cells. Journal of Bone and Mineral Research, 16 (8), pp. 1477-1485.

Griffin, Mark A., Patterson, Malcolm and West, Michael A. (2001). Job satisfaction and teamwork:The role of supervisor support. Journal of Organizational Behavior, 22 (5), pp. 537-550.

Skill, N. James, Griffin, Martin, El Nahas, A. Meguid, Sanai, Toru, Haylor, John L., Fisher, Marie, Jamie, Mathew F., Mould, Nigel N. and Johnson, Timothy S. (2001). Increases in renal ε-(γ-glutamyl)-lysine crosslinks result from compartment-specific changes in tissue transglutaminase in early experimental diabetic nephropathy:Pathologic implications. Laboratory Investigation, 81 (5), pp. 705-716.

Ball, Denise J., Mayhew, Stephen, Vernon, David I., Griffin, Martin and Brown, Stanley B. (2001). Decreased efficiency of trypsinization of cells following photodynamic therapy:evaluation of a role for tissue transglutaminase. Photochemistry and Photobiology, 73 (1), pp. 47-53.

Johnson, Timothy S., Griffin, Martin, Thomas, Graham L., Skill, James, Cox, Anne, Bin Yang, Ben, Nicholas, B., Birckbichler, Paul J., Muchaneta-Kubara, Chiwoneso and El Nahas, A.Meguid (1997). The role of transglutaminase in the rat subtotal nephrectomy model of renal fibrosis. Journal of Clinical Investigation, 99 (12), pp. 2950-2960.

Patent

Griffin, Martin (2011). Dipeptide inhibitors of angiogenesis. A61K38/05.

Collighan, Russell (2011). Novel Polypeptides and Use Thereof. A61K38/04.

This list was generated on Thu Mar 21 00:59:30 2019 GMT.