Browse by Aston Author

2023

Mulla, Suhayl, Ludlam, Adele R., Elragig, Aiman, Slack, Cathy, Balklava, Zita, Stich, Michael and Cheong, Alex (2023). A biphasic model of lifespan in nematode Caenorhabditis elegans worm. Royal Society Open Science, 10 (2), p. 220991.

2017

Cavadas, Miguel A.S., Cheong, Alex and Taylor, Cormac T. (2017). The regulation of transcriptional repression in hypoxia. Experimental Cell Research, 356 (2), pp. 173-181.

2016

Manresa, Mario Cabrero, Tambuwala, Murtaza M., Rhadakrishnan, Praveen, Harnoss, Jonathan M., Brown, Eric, Cavadas, Miguel A., Keogh, Ciara E., Cheong, Alex, Barrett, Kim E., Cummins, Eoin P., Schneider, Martin and Taylor, Cormac T. (2016). Hydroxylases regulate intestinal fibrosis through the suppression of ERK mediated TGF-β1 signaling. Gastrointestinal and Liver Physiology, 311 (6), G1076-G1090.

Cavadas, Miguel A.S., Mesnieres, Marion, Crifo, Bianca, Manresa, Mario C., Selfridge, Andrew C., Keogh, Ciara E., Fabian, Zsolt, Scholz, Carsten C., Nolan, Karen A., Rocha, Liliane M.A., Tambuwala, Murtaza M., Brown, Stuart, Wdowicz, Anita, Corbett, Danielle, Murphy, Keith J., Godson, Catherine, Cummins, Eoin P., Taylor, Cormac T. and Cheong, Alex (2016). REST is a hypoxia-responsive transcriptional repressor. Scientific Reports, 6 ,

2015

Cavadas, Miguel A.S., Mesnieres, Marion, Crifo, Bianca, Manresa, Mario C., Selfridge, Andrew C., Scholz, Carsten C., Cummins, Eoin P., Cheong, Alex and Taylor, Cormac T. (2015). REST mediates resolution of HIF-dependent gene expression in prolonged hypoxia. Scientific Reports, 5 ,

Nguyen, Lan K., Cavadas, Miguel A.S., Kholodenko, Boris N., Frank, Till D. and Cheong, Alex (2015). Species differential regulation of COX2 can be described by an NFκB-dependent logic AND gate. Cellular and Molecular Life Sciences, 72 (12), pp. 2431-2443.

2014

Dobrzyński, Maciej, Nguyen, Lan K., Birtwistle, Marc R., von Kriegsheim, Alexander, Fernández, Alfonso Blanco, Cheong, Alex, Kolch, Walter and Kholodenko, Boris N. (2014). Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responses. Journal of the Royal Society Interface, 11 (98),

2013

Scholz, Carsten C., Cavadas, Miguel A.S., Tambuwala, Murtaza M., Hams, Emily, Rodríguez, Javier, von Kriegsheim, Alexander, Cotter, Philip, Bruning, Ulrike, Fallon, Padraic G., Cheong, Alex, Cummins, Eoin P. and Taylor, Cormac T. (2013). Regulation of IL-1β-induced NFκB by hydroxylases links key hypoxic and inflammatory signaling pathways. Proceedings of the National Academy of Sciences, 110 (46), pp. 18490-18495.

Nguyen, Lan K., Cavadas, Miguel A.S., Scholz, Carsten C., Fitzpatrick, Susan F., Bruning, Ulrike, Cummins, Eoin P., Tambuwala, Murtaza M., Manresa, Mario C., Kholodenko, Boris N., Taylor, Cormac T. and Cheong, Alex (2013). A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network. Journal of Cell Science, 126 (6), pp. 1454-1463.

Cavadas, Miguel A.S., Nguyen, Lan K. and Cheong, Alex (2013). Hypoxia-inducible factor (HIF) network:insights from mathematical models. Cell Communication and Signaling, 11 (1),

2012

Frank, Till D., Cheong, Alex, Okada-Hatakeyama, Mariko and Kholodenko, Boris N. (2012). Catching transcriptional regulation by thermostatistical modeling. Physical Biology, 9 (4),

2011

Bruning, Ulrike, Cerone, Luca, Neufeld, Zoltan, Fitzpatrick, Susan F., Cheong, Alex, Scholz, Carsten C., Simpson, David A., Leonard, Martin O., Tambuwala, Murtaza M., Cummins, Eoin P. and Taylor, Cormac T. (2011). MicroRNA-155 promotes resolution of hypoxia-inducible factor 1α activity during prolonged hypoxia. Molecular and Cellular Biology, 31 (19), pp. 4087-4096.

Agbor, Terence A., Cheong, Alex, Comerford, Katrina M., Scholz, Carsten C., Bruning, Ulrike, Clarke, Ambrose, Cummins, Eoin P., Cagney, Gerard and Taylor, Cormac T. (2011). Small Ubiquitin-related Modifier (SUMO)-1 promotes glycolysis in hypoxia. Journal of Biological Chemistry, 286 (6), pp. 4718-4726.

Cheong, Alex, Li, Jing, Sukumar, Piruthivi, Kumar, Bhaskar, Zeng, Fanning, Riches, Kirsten, Munsch, Christopher, Wood, Ian C., Porter, Karen E. and Beech, David J. (2011). Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers. Cardiovascular Research, 89 (2), pp. 282-289.

2008

Tharp, D.L., Wamhoff, B.R., Wulff, H., Raman, G., Cheong, A. and Bowles, D.K. (2008). Local delivery of the KCa3.1 blocker, TRAM-34, prevents acute angioplasty-induced coronary smooth muscle phenotypic modulation and limits stenosis. Arteriosclerosis, Thrombosis, and Vascular biology, 28 (6), pp. 1084-1089.