Use of fluorescent optical fibre probe for recording parameters of brain metabolism in rat model

Alekseyev, Alexander, Seryogina, Evgeniya, Stelmashchuk, Olga, Zherebtsov, Evgeny A., Piavchenko, Gennadii, Vorobyev, Evgeny, Kuznetsova, Elena, Rafailov, Edik U., Kuznetsova, Alyona, Dunaev, Andrey, Rafailov, Ilya and Tuchin, Valery V. (2018). Use of fluorescent optical fibre probe for recording parameters of brain metabolism in rat model. IN: Proceedings of SPIE. Popp, Jürgen and Pavone, Francesco S. (eds) Proceedings of SPIE, 10685 . SPIE.

Abstract

This studiy was carried out on groups of clinically healthy male Wistar rats. Animals received distilled drinking water ad libitum for 1 month, water containing succinic acid, water containing zinc sulphate and succinate zinc. Using the method of fluorescence spectroscopy, the parameters of brain metabolism in vivo in a model of laboratory rats was investigated. Based on data obtained by fluorescence spectroscopy, we have registered a change in the degree of cellular respiration in different structures of the cerebral cortex with the toxic effect of zinc compounds and succinic acid on the oxygen exchange process.

Publication DOI: https://doi.org/10.1117/12.2290317
Divisions: Engineering & Applied Sciences
Engineering & Applied Sciences > Aston Institute of Photonics Technology
Engineering & Applied Sciences > Electrical, Electronic & Power Engineering
Additional Information: Copyright 2018 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Event Title: Biophotonics: Photonic Solutions for Better Health Care
Event Type: Other
Event Location: Strasbourg, France
Event Dates: 2018-04-22 - 2018-04-26
Full Text Link:
Related URLs: https://www.spi ... 12.2290317.full (Publisher URL)
PURE Output Type: Conference contribution
Published Date: 2018-05-17
Accepted Date: 2018-04-22
Authors: Alekseyev, Alexander
Seryogina, Evgeniya
Stelmashchuk, Olga
Zherebtsov, Evgeny A. ( 0000-0002-3635-1430)
Piavchenko, Gennadii
Vorobyev, Evgeny
Kuznetsova, Elena
Rafailov, Edik U. ( 0000-0002-4152-0120)
Kuznetsova, Alyona
Dunaev, Andrey
Rafailov, Ilya
Tuchin, Valery V.

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