Comparison of the influence of corneo-scleral and scleral lenses on ocular surface and tear film metrics in a presbyopic population


PURPOSE: To assess and compare the effect of the corneo-scleral lenses (C-ScL) and scleral lenses (ScL) on tear film parameters and central corneal thickness (CCT) in healthy presbyopic subjects. METHODS: Thirty subjects wore two contact lenses (CLs), randomly assigned, of neutral power, but of different diameters, 12.7mm (C-ScL) and 18mm (ScL) and being equal in the others parameters: material (HS100) and centre thickness (0.29mm). At baseline, 20min after insertion and at 8h, the tear meniscus area (TMA) and CCT was measured (with optical coherence tomography) as well as tear osmolarity. RESULTS: TMA revealed statistical differences for both lenses at 20min (p<0.001), and also at 8h (p=0.003), being greater for the C-ScL. CCT showed statistical differences for both lenses at 20min (p=0.002), and also at 8h (p=0.001), being lower for the C-ScL. Osmolarity did not reveal statistical differences at 20min (p=0.29), while it was statistically different at 8h (p=0.03), being lower for the C-ScL. CONCLUSIONS: C-ScL lead to a lesser reduction in the TMA and a lower induced hypoxic stress than the ScL. Osmolarity levels remained within normal values across the day with no clinical difference between lenses. Both designs can represent a good optical platform for correcting presbyopia as well as protecting the ocular surface by vaulting the cornea.

Publication DOI:
Divisions: Life & Health Sciences > Optometry
Life & Health Sciences > Ophthalmic Research Group
Life & Health Sciences
Life & Health Sciences > Vision, Hearing and Language
Additional Information: © 2017, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Funding: uropean Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No.642760 EDEN ITN-EJD Project Horizon 2020
Uncontrolled Keywords: Corneo-scleral lens,Scleral lens,Ocular surface,Presbyopia,Tear film
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Related URLs: https://www.sci ... 2357?via%3Dihub (Publisher URL)
PURE Output Type: Article
Published Date: 2018-02-01
Published Online Date: 2017-09-28
Accepted Date: 2017-09-08
Authors: Lafosse, Edouard
Romín, Daniel Monsálvez
Esteve-Taboada, José-Juan
Wolffsohn, James S ( 0000-0003-4673-8927)
Talens-Estarelles, Cristian
García-Lázaro, Santiago

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