DSM-5 Autism Spectrum Disorder:in search of essential behaviours for diagnosis

Carrington, Sarah J., Kent, Rachel G., Maljaars, Jarymke, Le Couteur, Ann, Gould, Judith, Wing, Lorna, Noens, Ilse, van Berckelaer-Onnes, Ina and Leekam, Susan R. (2014). DSM-5 Autism Spectrum Disorder:in search of essential behaviours for diagnosis. Research in autism spectrum disorders, 8 (6), pp. 701-715.

Abstract

The objective of this study was to identify a set of 'essential' behaviours sufficient for diagnosis of DSM-5 Autism Spectrum Disorder (ASD). Highly discriminating, 'essential' behaviours were identified from the published DSM-5 algorithm developed for the Diagnostic Interview for Social and Communication Disorders (DISCO). Study 1 identified a reduced item set (48 items) with good predictive validity (as measured using receiver operating characteristic curves) that represented all symptom sub-domains described in the DSM-5 ASD criteria but lacked sensitivity for individuals with higher ability. An adjusted essential item set (54 items; Study 2) had good sensitivity when applied to individuals with higher ability and performance was comparable to the published full DISCO DSM-5 algorithm. Investigation at the item level revealed that the most highly discriminating items predominantly measured social-communication behaviours. This work represents a first attempt to derive a reduced set of behaviours for DSM-5 directly from an existing standardised ASD developmental history interview and has implications for the use of DSM-5 criteria for clinical and research practice.

Publication DOI: https://doi.org/10.1016/j.rasd.2014.03.017
Divisions: Life & Health Sciences
Additional Information: © 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/)
Uncontrolled Keywords: abbreviaved,autism spectrum disorder,diagnosis,DISCO,DSM-5,Psychiatry and Mental health,Clinical Psychology,Developmental and Educational Psychology
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Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
Published Date: 2014-06
Authors: Carrington, Sarah J. ( 0000-0001-5548-8793)
Kent, Rachel G.
Maljaars, Jarymke
Le Couteur, Ann
Gould, Judith
Wing, Lorna
Noens, Ilse
van Berckelaer-Onnes, Ina
Leekam, Susan R.

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