Browse by Aston Author

Bailey, Clifford J. (2018). Glucose-lowering therapies in type 2 diabetes: Opportunities and challenges for peptides. Peptides, 100 , pp. 9-17.

Lascar, Nadia; Brown, James; Pattison, Helen; Barnett, Anthony H.; Bailey, Clifford J. and Bellary, Srikanth (2017). Type 2 diabetes in adolescents and young adults. The Lancet Diabetes and Endocrinology, in pre ,

Bailey, Clifford J. (2017). Metformin:historical overview. Diabetologia, 60 (9), 1566–1576.

Bailey, Clifford J. (2016). Under-treatment of type 2 diabetes:causes and outcomes of clinical inertia. International Journal of Clinical Practice, 70 (12), pp. 988-995.

McCreight, Laura J.; Bailey, Clifford J. and Pearson, Ewan R. (2016). Metformin and the gastrointestinal tract. Diabetologia, 59 (3), pp. 426-435.

Pararasa, Chathyan; Ikwuobe, John; Shigdar, Shahjahan; Boukouvalas, Alexis; Nabney, Ian T.; Brown, James E.; Devitt, Andrew; Bailey, Clifford J.; Bennett, Stuart J. and Griffiths, Helen R. (2016). Age-associated changes in long-chain fatty acid profile during healthy aging promote pro-inflammatory monocyte polarization via PPARγ. Aging Cell, 15 (1), pp. 128-139.

Pararasa, Chathyan; Bailey, Clifford J. and Griffiths, Helen R. (2015). Ageing, adipose tissue, fatty acids and inflammation. Biogerontology, 16 (2), pp. 235-248.

Qureshi, Khalid M.; Lee, Jou; Paget, Michelle B.; Bailey, Clifford J.; Curnow, S. John; Murray, Hilary E. and Downing, Richard (2015). Low gravity rotational culture and the integration of immunomodulatory stem cells reduce human islet allo-reactivity. Clinical Transplantation, 29 (1), pp. 90-98.

Day, Caroline and Bailey, Clifford J. (2015). Cardiovascular outcome trials in type 2 diabetes – 2015. Diabesity in practice, 4 (4), pp. 131-133.

Day, Caroline and Bailey, Clifford J. (2015). Pharmacotherapies to manage diabesity:an update. Diabesity in practice, 4 (1), pp. 14-23.

Home, Philip; Riddle, Matthew; Cefalu, William T.; Bailey, Clifford J.; Bretzel, Reinhard G.; del Prato, Stefano; Leroith, Derek; Schernthaner, Guntram; van Gaal, Luc and Raz, Itamar (2014). Response to comment on Home et al. Insulin therapy in people with type 2 diabetes:opportunities and challenges? Diabetes care 2014;37:1499-1508. Diabetes Care, 37 (11),

Bailey, Clifford J.; Azar, S.T.; Blonde, Lawrence; Dicker, D.; Puig-domingo, M; Eliaschewitz, F.G.; Nikonova, E.; Roussel, R.; Sakaguchi, K; Sauque-Reyna, L and Nauck, M. (2014). Relationship between changes in postprandial glucagon, patient characteristics, and response to lixisenatide as add-on to oral antidiabetics. Diabetologia, 57 (Suppl.), S344.

Fouqueray, Pascale; Pirags, Valdis; Diamant, Michaela; Schernthaner, Guntram; Lebovitz, Harold E.; Inzucchi, Silvio E. and Bailey, Clifford J. (2014). The efficacy and safety of imeglimin as add-on therapy in patients with type 2 diabetes inadequately controlled with sitagliptin monotherapy. Diabetes Care, 37 (7), pp. 1924-1930.

Home, Philip; Riddle, Matthew; Cefalu, William T.; Bailey, Clifford J.; Bretzel, Reinhard G.; del Prato, Stefano; Leroith, Derek; Schernthaner, Guntram; van Gaal, Luc and Raz, Itamar (2014). Insulin therapy in people with type 2 diabetes:opportunities and challenges? Diabetes Care, 37 (6), pp. 1499-1508.

Rana, Karan S.; Arif, Muhammad; Hill, Eric J.; Aldred, Sarah; Nagel, David A.; Nevill, Alan; Randeva, Harpal S.; Bailey, Clifford J.; Bellary, Srikanth and Brown, James E. (2014). Plasma irisin levels predict telomere length in healthy adults. Age, 36 (2), pp. 995-1001.

Al-Khattawi, Ali; Iyrie, Affiong; Dennison, Tom; Dahmash, Eman; Bailey, Clifford J.; Smith, Julian; Rue, Peter and Mohammed, Afzal R. (2014). Systematic screening of compressed ODT excipients:cellulosic versus non-cellulosic. Current Drug Delivery, 11 (4), pp. 486-500.

Paget, Michelle B.; Murray, Hilary E.; Bailey, Clifford J. and Downing, Richard (2013). Pre-transplant signal induction for vascularisation in human islets. Diabetes and Vascular Disease Research, 10 (6), pp. 536-545.

Tahrani, Abd A.; Barnett, Anthony H. and Bailey, Clifford J. (2013). SGLT inhibitors in management of diabetes. The Lancet Diabetes and Endocrinology, 1 (2), pp. 140-151.

Bailey, Clifford J.; Aschner, Pablo; del Prato, James; LaSalle, James; Ji, Linong and Matthaei, Stephan (2013). Individualized glycaemic targets and pharmacotherapy in type 2 diabetes. Diabetes and Vascular Disease Research, 10 (5), pp. 397-409.

Bailey, Clifford J. (2013). Interpreting adverse signals in diabetes drug development programs. Diabetes Care, 36 (7), pp. 2098-2106.

Bailey, Clifford J. (2013). Treatment with metformin. IN: The metabolic syndrome. Beck-Nielsen, Henning (ed.) Vienna (AT): Springer.

Fouqueray, Pascale; Pirags, Valdis; Inzucchi, Silvio E.; Bailey, Clifford J.; Schernthaner, Guntram; Diamant, Michaela and Lebovitz, Harold E. (2013). The efficacy and safety of imeglimin as add-on therapy in patientswith type 2 diabetes inadequately controlled with metformin monotherapy. Diabetes Care, 36 (3), pp. 565-568.

Gao, Dan; Pararasa, Chathyan; Dunston, Christopher R; Bailey, Clifford J. and Griffiths, Helen R. (2012). Palmitate promotes monocyte atherogenicity via de novo ceramide synthesis. Free Radical Biology and Medicine, 53 (4), 796–806.

Bailey, Clifford J. (2012). Diabetes : insulin plus metformin for T2DM-are there benefits? Nature Reviews Endocrinology, 8 (8), pp. 449-450.

Bailey, Clifford J.; Day, Caroline; Campbell, Ian W. and Schindler, Christoph (2012). Glycaemic control and cardiovascular outcome trials in type 2 diabetes. British Journal of Diabetes and Vascular Disease, 12 (4), pp. 161-164.

Tahrani, Abd A.; Bailey, Clifford J. and Barnett, Anthony H. (2012). Insulin degludec:a new ultra-longacting insulin. The Lancet, 379 (9825), pp. 1465-1467.

Day, Caroline and Bailey, Clifford J. (2012). The hypocaloric diet in type 2 diabetes - déjà vu. British Journal of Diabetes and Vascular Disease, 12 (1), pp. 48-51.

Day, Caroline and Bailey, Clifford J. (2011). Metformin. IN: xPharm. Enna, S.J. and Bylund, David B. (eds) Elsevier.

Day, Caroline and Bailey, Clifford J. (2011). Pioglitazone. IN: xPharm. Enna, S.J. and Bylund, David B. (eds) Elsevier.

Day, Caroline and Bailey, Clifford J. (2011). Obesity in the pathogenesis of type 2 diabetes. British Journal of Diabetes and Vascular Disease, 11 (2), pp. 55-61.

Day, Caroline and Bailey, Clifford J. (2011). Biguanides. IN: xPharm. Enna, S.J. and Bylund, David B. (eds) Elsevier.

Day, Caroline and Bailey, Clifford J. (2011). Ciglitazone. IN: xPharm. Enna, S.J. and Bylund, David B. (eds) Elsevier.

Day, Caroline and Bailey, Clifford J. (2011). Rosiglitazone. IN: xPharm. Enna, S.J. and Bylund, David B. (eds) Elsevier.

Bailey, Clifford J. (2011). Thiazolidinediones. IN: xPharm. Enna, S.J. and Bylund, David B. (eds) Elsevier.

Day, Caroline and Bailey, Clifford J. (2011). Troglitazone. IN: xPharm. Elsevier.

Qureshi, Khalid M.; Oliver, Robert J.; Paget, Michelle B; Murray, Hilary E; Bailey, Clifford J. and Downing, Richard (2011). Human amniotic epithelial cells induce localized cell-mediated immune privilege in vitro:implications for pancreatic islet transplantation. Cell Transplantation, 20 (4), pp. 523-534.

Bailey, Clifford J.; Green, Brian D. and Flatt, Peter R. (2010). Fixed-dose combination therapy for type 2 diabetes:sitagliptin plus pioglitazone. Expert Opinion on Investigational Drugs: authoritative analysis of r and d trends, 19 (8), pp. 1017-1025.

Bailey, Clifford J. (2010). Future drug treatments for type 2 diabetes. IN: Textbook of diabetes. Holt, Richard I.G.; Cockram, Clive S.; Flyvbjerg, Allan and Goldstein, Barry J. (eds) Wiley-Blackwell.

Bailey, Clifford J. and Krentz, Andrew J. (2010). Oral antidiabetic agents. IN: Textbook of diabetes. Holt, Richard I.G.; Cockram, Clive S.; Flyvbjerg, Allan and Goldstein, Barry J. (eds) Wiley-Blackwell.

Bailey, Clifford J.; Gross, Jorge L.; Pieters, Anne; Bastien, Arnaud and List, James F. (2010). Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin:a randomised, double-blind, placebo-controlled trial. The Lancet, 375 (9733), pp. 2223-2233.

Bailey, Clifford J. and Barnett, Anthony H. (2010). Inhaled insulin:new formulation, new trial. The Lancet, 375 (9733), pp. 2199-201.

Bergenstal, Richard M.; Bailey, Clifford J. and Kendall, David M. (2010). Type 2 diabetes:assessing the relative risks and benefits of glucose-lowering medications. American Journal of Medicine, 123 (4), 374.e9-374.e18.

Bailey, Clifford J. and Day, Caroline (2010). Hypoglycaemia:a limiting factor. British Journal of Diabetes and Vascular Disease, 10 (1), pp. 2-4.

Gao, Dan; Bailey, Clifford J. and Griffiths, Helen R. (2009). Metabolic memory effect of the saturated fatty acid, palmitate, in monocytes. Biochemical and Biophysical Research Communications, 388 (2), pp. 278-282.

Tan, Bee K.; Chen, Jing; Adya, Raghu; Ramanjaneya, Manjunath; Menon, Vinod; Bailey, Clifford J.; Brown, James; Lehnert, Hendrik and Randeva, Harpal S. (2009). In vivo and ex vivo regulation of visfatin production by leptin in human and murine adipose tissue: role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways. Endocrinology, 150 (8), pp. 3530-3539.

Day, Caroline and Bailey, Clifford J. (2009). HbA1c - changing units. British Journal of Diabetes and Vascular Disease, 9 (3), pp. 134-136.

Flatt, Peter R.; Day, Caroline and Bailey, Clifford J. (2009). Review: bariatric surgery:to treat diabesity. British Journal of Diabetes and Vascular Disease, 9 (3), pp. 103-107.

Krentz, Andrew J.; Patel, Mayank B. and Bailey, Clifford J. (2008). New drugs for type 2 diabetes mellitus:what is their place in therapy? Drugs, 68 (15), pp. 2131-2162.

Bailey, Clifford J. (2008). Metformin:effects on micro and macrovascular complications in type 2 diabetes. Cardiovascular Drugs and Therapy, 22 (3), pp. 215-224.

Bailey, Clifford J.; Barnett, Anthony H. and Petrie, John R. (2008). Value of glycaemic control in diabetes. The Lancet, 371 (9607), p. 116.

Bailey, Clifford J. and Barnett, Anthony H. (2007). Why is Exubera being withdrawn? BMJ, 335 (7630), p. 1156.

Bailey, Clifford J.; Barnett, Anthony H. and Day, Caroline (2007). Exubera expires. British Journal of Diabetes and Vascular Disease, 7 (6), pp. 255-256.

Day, Caroline and Bailey, Clifford J. (2007). Glycaemic control IS important. British Journal of Diabetes and Vascular Disease, 7 (5), pp. 197-198.

Bailey, Clifford J. (2007). Learning from tesaglitazar. Diabetes and Vascular Disease Research, 4 (3), pp. 161-162.

Gao, Dan; Griffiths, Helen R. and Bailey, Clifford J. (2007). Palmitate induces insulin resistance in monocytes and increases expression of the integrin CD11b. IN: Scientific Meeting of the Nutrition Society. 2007-07-01. (Unpublished)

O'Harte, Finbarr P.M.; Hunter, Kerry; Gault, Victor A.; Irwin, Nigel; Green, Brian D.; Greer, Brett; Harriott, Patrick; Bailey, Clifford J. and Flatt, Peter R. (2007). Antagonistic effects of two novel GIP analogs, (Hyp3)GIP and (Hyp3)GIPLys16PAL, on the biological actions of GIP and longer-term effects in diabetic ob/ob mice. American Journal of Physiology, 292 (6), E1674-E1682.

Bailey, Clifford J.; Day, Caroline and Campbell, Ian W. (2006). A consensus algorithm for treating hyperglycaemia in type 2 diabetes. British Journal of Diabetes and Vascular Disease, 6 (4), pp. 147-148.

Bailey, Clifford J. (1973). Studies on the influence of sex hormones on glucose tolerance and insulin secretion in the rat. PHD thesis, Aston University.

McKiney, Joan M.; Irwin, Nigel; Flatt, Peter R.; Bailey, Clifford J. and McClenaghan, Neville H. Acute and long-term effects of metformin on the function and insulin secretory responsiveness of clonal β-cells. Biological Chemistry, 391 (12), pp. 1451-1459.

Evans, Mark; Cranston, Iain and Bailey, Clifford J. Ambulatory glucose profile (AGP):utility in UK clinical practice. British Journal of Diabetes and Vascular Disease, 17 (1), pp. 26-33.

Bailey, Clifford J. and Day, Caroline Anti-obesity fixed-dose combinations. British Journal of Diabetes and Vascular Disease, 12 (1), pp. 2-5.

Bailey, Clifford J. and Alberti, K. G M M Cardio-diabetes alliances. Diabetes and Vascular Disease Research, 4 (1), pp. 5-6.

Bailey, Clifford J.; Gross, Jorge L.; Hennicken, Delphine; Iqbal, Nayyar; Mansfield, Traci A. and List, James F. Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin:a randomized, double-blind, placebo-controlled 102-week trial. BMC Medicine, 11 (1),

Irwin, Nigel; Green, Brian D.; Gault, Victor A.; Greer, Brett; Harriott, Patrick; Bailey, Clifford J.; Flatt, Peter R. and O'Harte, Finbarr P.M. Degradation, insulin secretion, and antihyperglycemic actions of two palmitate-derivitized N-terminal pyroglutamyl analogues of glucose-dependent insulinotropic polypeptide. Journal of Medicinal Chemistry, 48 (4), pp. 1244-1250.

Bailey, Clifford J. and Day, Caroline Diabetes therapies in renal impairment. British Journal of Diabetes and Vascular Disease, 12 (4), pp. 167-171.

Flatt, Peter R.; Bailey, Clifford J. and Green, Brian D. Dipeptidyl peptidase IV (DPP IV) and related molecules in type 2 diabetes. Frontiers in Bioscience, 13 (10), pp. 3648-3660.

Day, Caroline and Bailey, Clifford J. Editorial : which weight loss diet? British Journal of Diabetes and Vascular Disease, 9 (2), p. 43.

Day, Caroline; Campbell, Ian W. and Bailey, Clifford J. Free to publish - free to read. British Journal of Diabetes and Vascular Disease, 13 (4), pp. 162-163.

Bailey, Clifford J.; Tahrani, Abd A. and Barnett, Anthony H. Future glucose-lowering drugs for type 2 diabetes. The Lancet Diabetes and Endocrinology, 4 (4), pp. 350-359.

Irwin, Nigel; O'Harte, Finbarr P.M.; Gault, Victor A.; Green, Brian D.; Greer, Brett; Harriott, Patrick; Bailey, Clifford J. and Flatt, Peter R. GIP(Lys16PAL) and GIP(LyS37PAL):novel long-acting acylated analogues of glucose-dependent insulinotropic polypeptide with improved antidiabetic potentia. Journal of Medicinal Chemistry, 49 (3), pp. 1047-1054.

Bailey, Clifford J. and Day, Caroline Glycaemic memory. British Journal of Diabetes and Vascular Disease, 8 (5), pp. 242-247.

Bailey, Clifford J. Metformin. IN: Therapy for diabetes mellitus and related disorders. Umpierrez, Guillermo E. (ed.) Alexandria, VA (US): American Diabetes Association.

Inzucchi, Silvio E.; Lipska, Kasia J.; Mayo, Helen; Bailey, Clifford J. and McGuire, Darren K. Metformin in patients with type 2 diabetes and kidney disease:a systematic review. JAMA: Journal of the American Medical Association, 312 (24), pp. 2668-2675.

Green, Brian D.; Lavery, Kerry S.; Irwin, Nigel; O'Harte, Finbarr P.M.; Harriott, Patrick; Greer, Brett; Bailey, Clifford J. and Flatt, Peter R. Novel glucagon-like peptide-1 (GLP-1) analog (Val8)GLP-1 results in significant improvements of glucose tolerance and pancreatic β-cell function after 3-week daily administration in obese diabetic (ob/ob) mice. Journal of Pharmacology and Experimental Therapeutics, 318 (2), pp. 914-921.

Gao, Dan; Griffiths, Helen R. and Bailey, Clifford J. Oleate protects against palmitate-induced insulin resistance in L6 myotubes. British Journal of Nutrition, 102 (11), pp. 1557-1563.

Tahrani, Abd A.; Barnett, Anthony H. and Bailey, Clifford J. Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus. Nature Reviews Endocrinology, 12 (10), 566–592.

Cooper, Michael B.; Al Majali, Khulood; Bailey, Clifford J. and Betteridge, D. John Reduced postprandial proinsulinaemia and 32-33 split proinsulinaemia after a mixed meal in type 2 diabetic patients following sensitization to insulin with pioglitazone. Clinical Endocrinology, 68 (5), pp. 738-746.

Bailey, Clifford J. and Day, Caroline SGLT2 inhibitors:glucuretic treatment for type 2 diabetes. British Journal of Diabetes and Vascular Disease, 10 (4), pp. 193-199.

Murray, H.E.; Paget, Michelle B.; Bailey, Clifford J. and Downing, R. Sustained insulin secretory response in human islets co-cultured with pancreatic duct-derived epithelial cells within a rotational cell culture system. Diabetologia, 52 (3), pp. 477-485.

Bailey, Clifford J. Timely intervention in type 2 diabetes:achieving early and sustained glycemic control. Medicographia, 38 (1), pp. 3-8.

Bailey, Clifford J. The challenge of managing coexistent type 2 diabetes and obesity. BMJ, 342 (7803),

McGill, Margaret; Blonde, Lawrence; Chan, Juliana C.N.; Khunti, Kamlesh; Lavalle, Fernando J. and Bailey, Clifford J. The interdisciplinary team in type 2 diabetes management:challenges and best practice solutions from real-world scenarios. Journal of Clinical and Translational Endocrinology, 7 , pp. 21-27.

Naujok, Ortwin; Francini, Flavio; Picton, Sally; Jörns, Anne; Lenzen, Sigurd and Bailey, Clifford J. A new experimental protocol for preferential differentiation of mouse embryonic stem cells into insulin-producing cells. Cell Transplantation, 17 (10-11), pp. 1231-1242.