Wearable laser Doppler flowmetry for the analysis of microcirculatory changes during intravenous infusion in patients with diabetes mellitus

Abstract

The article is aimed at conducting pilot studies of microcirculation changes in patients with diabetes mellitus during the course of intravenous infusions of alpha lipoic acid. The study was conducted with patients with diabetes during the passage of a standard course of treatment. The change in parameters was compared before the start of the infusion course, during and after the course. A system of wearable laser Doppler monitors was used to conduct the study. The study showed that although the microcirculation index does not undergo significant changes during the treatment process, spectral analysis of the recorded signal has potential applicability. Further studies with a larger sample group are required for a qualitative analysis of the observed effects.

Publication DOI: https://doi.org/10.1117/12.2552464
Divisions: Engineering & Applied Sciences > Aston Institute of Photonics Technology
Additional Information: Copyright 2020 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. Funding Information: This study was funded by the Russian Science Foundation (the research project 18-79-00237).
Uncontrolled Keywords: Alpha lipoic acid,Diabetic neuropathy,Laser Doppler flowmetry,Skin blood flow,Wearable electronics,Electronic, Optical and Magnetic Materials,Condensed Matter Physics,Computer Science Applications,Applied Mathematics,Electrical and Electronic Engineering
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.spi ... 12.2552464.full (Publisher URL)
PURE Output Type: Conference article
Published Date: 2020-04-02
Authors: Zharkikh, Elena V.
Loktionova, Yulia I.
Kozlov, Igor O.
Zherebtsova, Angelina I.
Sidorov, Victor V.
Zherebtsov, Evgeny A.
Dunaev, Andrey V.
Rafailov, Edik U. (ORCID Profile 0000-0002-4152-0120)

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