Fiber-optic system for intraoperative study of abdominal organs during minimally invasive surgical interventions


The paper presents the results of experimental measurements of endogenous fluorescence and blood perfusion in patients with pathology of the organs of hepatopancreatoduodenal area in vivo. A custom setup combining channels for fluorescence spectroscopy (excitation wavelengths of 365 nm and 450 nm) and laser Doppler flowmetry (1064 nm) with fibre optical probe for nondestructive laparoscopic measurements has been developed and applied during minimally invasive operation procedure. Preliminary measurements with two aforementioned channels have been performed at specified excitation wavelengths. The possibility of obtaining fluorescence spectra and laser Doppler flowmetry signals in vivo during minimally invasive interventions was shown. Obtained data show perspectives of further research on technical and methodological development of optical diagnostic methods for minimally invasive surgery. The obtained results can be used to provide a deeper understanding of pathological processes influence on optical properties of abdominal organs tissues, which will ultimately help surgeons to determine the state of vitality in tissues and mucous membranes directly during the process of surgical intervention.

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Divisions: Engineering & Applied Sciences > Aston Institute of Photonics Technology
Additional Information: © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (
Uncontrolled Keywords: Fluorescence spectroscopy,Hepatopancreatoduodenal area,Laser Doppler flowmetry,Minimally invasive surgery,Optical biopsy,Optical non-invasive diagnostics,Materials Science(all),Instrumentation,Engineering(all),Process Chemistry and Technology,Computer Science Applications,Fluid Flow and Transfer Processes
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Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.mdp ... 76-3417/9/2/217 (Publisher URL)
PURE Output Type: Article
Published Date: 2019-01-09
Accepted Date: 2019-01-03
Authors: Kandurova, Ksenia
Dremin, Viktor (ORCID Profile 0000-0001-6974-3505)
Zherebtsov, Evgeny
Potapova, Elena
Alyanov, Alexander
Mamoshin, Andrian
Ivanov, Yury
Borsukov, Alexey
Dunaev, Andrey



Version: Published Version

License: Creative Commons Attribution

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