Femtosecond laser inscribed advanced calibration phantom for optical coherence tomography (OCT)

Abstract

Optical coherence tomography (OCT) has developed rapidly and is widely used in different fields such as biomedicine and optometry. The characterization and calibration of OCT systems is essential when testing the system and during normal use to ensure that there is no misalignment or distortion that could affect clinical decisions. Imaging distortion is a significant challenge for OCT systems when viewing through non-planar surfaces. Here we present a new multi-purpose plano-convex OCT phantom which is designed to be used for OCT characterization and calibration as well as to validate the post-processing algorithm for the imaging distortion of the OCT systems. A femtosecond laser direct writing technique is used to fabricate this phantom which consists of a landmark layer with radial lines at a 45-degree angular spacing inscribed at 50μm in apparent depth (AD) underneath the planar surface. Below that there are a further 8 layers of a spherical inscription pattern which has a 150μm (in AD) separation between each layer. The first spherical layer is located at 150μm (in AD) underneath the planar surface. Due to the laser power loss when travelling through the deeper layer, an increased power is applied to the deeper layers. The spherical pattern overcomes orientation issues seen with existing calibration phantoms. The landmark layer is applied so that it can easily tell the exact location when scanning which will also benefit the image distortion correction process.

Publication DOI: https://doi.org/10.1117/12.2544310
Divisions: Engineering & Applied Sciences > Electrical, Electronic & Power Engineering
Life & Health Sciences > Biosciences
Engineering & Applied Sciences > Aston Institute of Photonics Technology
Engineering & Applied Sciences
Engineering & Applied Sciences > Mechanical Engineering & Design
Additional Information: Copyright 2020 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Event Title: Advanced Fabrication Technologies for Micro/Nano Optics and Photonics XIII 2020
Event Type: Other
Event Dates: 2020-02-02 - 2020-02-05
Uncontrolled Keywords: Femtosecond laser direct writing,Femtosecond laser inscription,OCT calibration phantom,OCT image distortion,OCT phantom,OCT phantom fabrication,Optical coherence tomography (OCT),Electronic, Optical and Magnetic Materials,Condensed Matter Physics,Computer Science Applications,Applied Mathematics,Electrical and Electronic Engineering
ISBN: 9781510633476
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.spi ... 310.short?SSO=1 (Publisher URL)
PURE Output Type: Conference contribution
Published Date: 2020-02-28
Accepted Date: 2020-01-01
Authors: Lu, Yang
Gordon, Neil
Coldrick, Benjamin ( 0000-0003-0969-7062)
Ibrahim, Izzati
Mezentsev, Vladimir ( 0000-0002-8415-1767)
Robinson, David
Sugden, Kate ( 0000-0001-6323-1082)

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