Grant, Lois, Milic, Ivana and Devitt, Andrew (2019). Apoptotic cell-derived extracellular vesicles: structure-function relationships. Biochemical Society Transactions, 47 (2), pp. 509-516.
Abstract
Apoptosis is an essential process for normal physiology and plays a key role in the resolution of inflammation. Clearance of apoptotic cells (ACs) involves complex signalling between phagocytic cells, ACs, and the extracellular vesicles (EVs) they produce. Here, we discuss apoptotic cell-derived extracellular vesicles (ACdEVs) and how their structure relates to their function in AC clearance and the control of inflammation, focussing on the ACdEV proteome. We review the current knowledge, ongoing work and future directions for research in this field.
| Publication DOI: | https://doi.org/10.1042/BST20180080 |
|---|---|
| Divisions: | College of Health & Life Sciences > School of Biosciences College of Health & Life Sciences College of Health & Life Sciences > School of Biosciences > Cell & Tissue Biomedical Research College of Health & Life Sciences > Chronic and Communicable Conditions College of Health & Life Sciences > School of Biosciences > Cellular and Molecular Biomedicine |
| Additional Information: | © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society |
| Uncontrolled Keywords: | extracellular vesicles,macrophages,phagocytosis,Biochemistry |
| Publication ISSN: | 1470-8752 |
| Last Modified: | 11 Mar 2024 08:27 |
| Date Deposited: | 19 Aug 2019 09:39 |
| Full Text Link: | |
| Related URLs: |
http://www.bioc ... 0.full-text.pdf
(Publisher URL) http://www.scop ... tnerID=8YFLogxK (Scopus URL) |
PURE Output Type: | Review article |
| Published Date: | 2019-04-30 |
| Published Online Date: | 2019-04-05 |
| Accepted Date: | 2019-04-01 |
| Authors: |
Grant, Lois
Milic, Ivana ( 
0000-0001-7531-7561)
Devitt, Andrew (
0000-0002-4651-6761)
|
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)