GPCRTree:online hierarchical classification of GPCR function

Abstract

G protein-coupled receptors (GPCRs) play important physiological roles transducing extracellular signals into intracellular responses. Approximately 50% of all marketed drugs target a GPCR. There remains considerable interest in effectively predicting the function of a GPCR from its primary sequence.

Publication DOI: https://doi.org/10.1186/1756-0500-1-67
Divisions: College of Health & Life Sciences > Aston Pharmacy School
College of Health & Life Sciences
College of Health & Life Sciences > Chronic and Communicable Conditions
Additional Information: © 2008 Davies et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Uncontrolled Keywords: Biochemistry, Genetics and Molecular Biology(all),Medicine(all)
Publication ISSN: 1756-0500
Last Modified: 03 Jan 2024 08:05
Date Deposited: 19 Aug 2019 08:53
Full Text Link: http://www.biom ... /1756-0500/1/67
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2008-08-21
Authors: Davies, Matthew N.
Secker, Andrew
Halling-Brown, Mark
Moss, David S.
Freitas, Alex A.
Timmis, Jon
Clark, Edward
Flower, Darren R (ORCID Profile 0000-0002-8542-7067)

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