Rotational and centration stability of an aspheric intraocular lens with a simulated toric design


Purpose: To assess the stability of the Akreos AO intraocular lens (IOL) platform with a simulated toric design using objective image analysis. Setting: Six hospital eye clinics across Europe. Methods: After implantation in 1 eye of patients, IOLs with orientation marks were imaged at 1 to 2 days, 7 to 14 days, 30 to 60 days, and 120 to 180 days. The axis of rotation and IOL centration were objectively assessed using validated image analysis. Results: The study enrolled 107 patients with a mean age of 69.9 years ± 7.7 (SD). The image quality was sufficient for IOL rotation analysis in 91% of eyes. The mean rotation between the first day postoperatively and 120 to 180 days was 1.93 ± 2.33 degrees, with 96% of IOLs rotating fewer than 5 degrees and 99% rotating fewer than 10 degrees. There was no significant rotation between visits and no clear bias in the direction of rotation. In 71% of eyes, the dilation and image quality was sufficient for image analysis of centration. The mean change in centration between 1 day and 120 to 180 days was 0.21 ± 0.11 mm, with all IOLs decentering less than 0.5 mm. There was no significant decentration between visits and no clear bias in the direction of the decentration. Conclusion: Objective analysis of digital retroillumination images taken at different postoperative periods shows the aspheric IOL platform was stable in the eye and is therefore suitable for the application of a toric surface to correct corneal astigmatism.

Publication DOI:
Divisions: Life & Health Sciences > Ophthalmic Research Group
Life & Health Sciences > Vision, Hearing and Language
Life & Health Sciences
Life & Health Sciences > Optometry
Additional Information: NOTICE: this is the author’s version of a work that was accepted for publication in the Journal of Cataract & Refractive Surgery. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Buckhurst, PJ, Wolffsohn, JS, Naroo, SA & Davies, LN, 'Rotational and centration stability of an aspheric intraocular lens with a simulated toric design', Journal of cataract and refractive surgery, vol 36, no. 9 (2010) DOI
Uncontrolled Keywords: Aged,Aged, 80 and over,Astigmatism,Female,Humans,Lens Implantation, Intraocular,Lenses, Intraocular,Male,Middle Aged,Phacoemulsification,Prosthesis Design,Prosthesis Failure,Refraction, Ocular,Rotation,Ophthalmology,Surgery,Sensory Systems
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Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2010-09
Published Online Date: 2010-08-06
Authors: Buckhurst, Phillip J.
Wolffsohn, James S. ( 0000-0003-4673-8927)
Naroo, Shehzad A. ( 0000-0002-6373-7187)
Davies, Leon N. ( 0000-0002-1554-0566)



Version: Accepted Version

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