GPCRTree:online hierarchical classification of GPCR function

Davies, Matthew N., Secker, Andrew, Halling-Brown, Mark, Moss, David S., Freitas, Alex A., Timmis, Jon, Clark, Edward and Flower, Darren R (2008). GPCRTree:online hierarchical classification of GPCR function. BMC Research Notes, 1 , p. 67.


G protein-coupled receptors (GPCRs) play important physiological roles transducing extracellular signals into intracellular responses. Approximately 50% of all marketed drugs target a GPCR. There remains considerable interest in effectively predicting the function of a GPCR from its primary sequence.

Publication DOI:
Divisions: Life & Health Sciences > Pharmacy
Life & Health Sciences
Additional Information: © 2008 Davies et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Uncontrolled Keywords: Biochemistry, Genetics and Molecular Biology(all),Medicine(all)
Full Text Link: http://www.biom ... /1756-0500/1/67
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
Published Date: 2008-08-21
Authors: Davies, Matthew N.
Secker, Andrew
Halling-Brown, Mark
Moss, David S.
Freitas, Alex A.
Timmis, Jon
Clark, Edward
Flower, Darren R ( 0000-0002-8542-7067)



Version: Published Version

License: Creative Commons Attribution

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