Psychophysical evidence for two routes to suppression before binocular summation of signals in human vision


Visual mechanisms in primary visual cortex are suppressed by the superposition of gratings perpendicular to their preferred orientations. A clear picture of this process is needed to (i) inform functional architecture of image-processing models, (ii) identify the pathways available to support binocular rivalry, and (iii) generally advance our understanding of early vision. Here we use monoptic sine-wave gratings and cross-orientation masking (XOM) to reveal two cross-oriented suppressive pathways in humans, both of which occur before full binocular summation of signals. One is a within-eye (ipsiocular) pathway that is spatially broadband, immune to contrast adaptation and has a suppressive weight that tends to decrease with stimulus duration. The other pathway operates between the eyes (interocular), is spatially tuned, desensitizes with contrast adaptation and has a suppressive weight that increases with stimulus duration. When cross-oriented masks are presented to both eyes, masking is enhanced or diminished for conditions in which either ipsiocular or interocular pathways dominate masking, respectively. We propose that ipsiocular suppression precedes the influence of interocular suppression and tentatively associate the two effects with the lateral geniculate nucleus (or retina) and the visual cortex respectively. The interocular route is a good candidate for the initial pathway involved in binocular rivalry and predicts that interocular cross-orientation suppression should be found in cortical cells with predominantly ipsiocular drive. © 2007 IBRO.

Publication DOI:
Divisions: Life & Health Sciences > Optometry
Life & Health Sciences > Clinical and Systems Neuroscience
Life & Health Sciences > Centre for Vision and Hearing Research
Additional Information: NOTICE: this is the author’s version of a work that was accepted for publication in Neuroscience. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Baker, Daniel H.; Meese, Timothy S. and Summers, Robert J. (2007). Psychophysical evidence for two routes to suppression before binocular summation of signals in human vision. Neuroscience, 146 (1), pp. 435-448. DOI 10.1016/j.neuroscience.2007.01.030
Uncontrolled Keywords: binocular rivalry,contrast gain control,cross-orientation inhibition,human vision,masking,psychophysics,Neuroscience(all)
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2007-03-07
Authors: Baker, Daniel H.
Meese, Timothy S. ( 0000-0003-3744-4679)
Summers, Robert J. ( 0000-0003-4857-7354)


Export / Share Citation


Additional statistics for this record