Dipeptide inhibitors of angiogenesis


The present invention relates to inhibitors of tissue transglutaminase for use in the inhibition of angiogenesis in a subject. In particular, the invention provides compounds of Formula I for use in the treatment and/or prevention of angiogenic diseases and disorders of the eye, such as diabetic retinopathy and age-related macular degeneration (AMD). The invention further provides methods for inhibiting angiogenesis in a subject.

Publication DOI: A61K38/05
Divisions: Life & Health Sciences > Biosciences
Life & Health Sciences
Life & Health Sciences > Chronic and Communicable Conditions
Life & Health Sciences > Cellular and Molecular Biomedicine
Aston University (General)
Full Text Link: http://worldwid ... 25A1&KC=A1&ND=4
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PURE Output Type: Patent
Published Date: 2011-05-06
Authors: Griffin, Martin
Perez, Mileidys

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