Chromatography of oxysterols

Dias, Irundika H.k., Wilson, Steven R. and Roberg-larsen, Hanne (2018). Chromatography of oxysterols. Biochimie ,


Oxysterols play important roles in development and diseases, but can be highly challenging to analyze. To ensure satisfactory measurements, oxysterols must typically be separated with chromatography prior to detection. Here, we will devote attention to the chromatography of oxysterols, focusing on gas chromatography and liquid chromatography. We will present the role of stationary phases, mobile phases, and dimensions and geometries of particles/columns. We discuss how these parameters may affect the chromatography, regarding factors such as speed and resolution. Finally, we present some less explored avenues for separation of oxysterols.

Publication DOI:
Divisions: Life & Health Sciences
Life & Health Sciences > Chronic and Communicable Conditions
Life & Health Sciences > Psychology
Life & Health Sciences > Cell & Tissue Biomedical Research
Additional Information: © 2018, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Funding: Kidney Research Foundation PDF3/2014 and Alzheimer's Research UK network grants.
Uncontrolled Keywords: (max 6)Oxysterols,Chromatography,Separation,Lipids,Sterols
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Related URLs: https://www.sci ... 300908418301275 (Publisher URL)
Published Date: 2018-05-09
Published Online Date: 2018-05-09
Authors: Dias, Irundika H.k. ( 0000-0002-6620-8221)
Wilson, Steven R.
Roberg-larsen, Hanne

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