Tunable Ag@SiO2 core-shell nanocomposites for broad spectrum antibacterial applications

Abstract

Silica encapsulated silver nanoparticle core-shell nanocomposites of tunable dimensions were synthesised via a one-pot reverse microemulsion route to achieve controlled release of Ag+ ions for broad spectrum antibacterial application. Silver release rates and bactericidal efficacy against Gram-positive and Gram-negative bacteria, S. aureus and P. aeruginosa respectively, were inversely proportional to nanoparticle core diameter (3-8 nm) and silica shell (7-14 nm) thickness, and readily tuned through a facile hydrothermal etching protocol employing a PVP stabiliser to introduce mesoporosity.

Publication DOI: https://doi.org/10.1039/c7ra03131a
Divisions: Engineering & Applied Sciences
Life & Health Sciences > Biosciences
Life & Health Sciences
Life & Health Sciences > Chronic and Communicable Conditions
Life & Health Sciences > Cell & Tissue Biomedical Research
Engineering & Applied Sciences > Chemical Engineering & Applied Chemistry
Engineering & Applied Sciences > Energy and Bioproducts Research Institute (EBRI)
Additional Information: This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Uncontrolled Keywords: Chemistry(all),Chemical Engineering(all)
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2017-04-27
Accepted Date: 2017-04-20
Submitted Date: 2017-03-16
Authors: Isaacs, Mark A.
Durndell, Lee J.
Hilton, Anthony C. ( 0000-0001-8025-5270)
Olivi, Luca
Parlett, Christopher M.A. ( 0000-0002-3651-7314)
Wilson, Karen ( 0000-0003-4873-708X)
Lee, Adam F.

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