Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment

Abstract

Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.

Publication DOI: https://doi.org/10.1021/acsbiomaterials.6b00705
Divisions: College of Engineering & Physical Sciences > School of Infrastructure and Sustainable Engineering > Chemical Engineering & Applied Chemistry
College of Engineering & Physical Sciences > Energy and Bioproducts Research Institute (EBRI)
Additional Information: This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Biomaterials Science and Engineering, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/acsbiomaterials.6b00705
Uncontrolled Keywords: biofilm,fibroblast,plasma,polymerization,polyurethane,XPS,Biomaterials,Biomedical Engineering
Last Modified: 25 Mar 2024 08:21
Date Deposited: 19 Apr 2017 08:45
Full Text Link:
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
PURE Output Type: Article
Published Date: 2017-01-09
Published Online Date: 2016-12-12
Accepted Date: 2016-12-12
Submitted Date: 2016-11-14
Authors: Watkins, Lucy M.
Lee, Adam F. (ORCID Profile 0000-0002-2153-1391)
Moir, James W.B.
Wilson, Karen (ORCID Profile 0000-0003-4873-708X)

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