Systemic inflammatory impact of periodontitis on acute coronary syndrome

Widén, Cecilia, Holmer, Helene, Coleman, Michael, Tudor, Marian, Ohlsson, Ola, Sättlin, Susanna, Renvert, Stefan and Persson, Goesta Rutger (2016). Systemic inflammatory impact of periodontitis on acute coronary syndrome. Journal of Clinical Periodontology, 43 (9), pp. 713-719.

Abstract

Aim: A causative relationship between acute coronary syndrome (ACS) and periodontitis has yet to be defined. The aim of this study was to assess differences in levels of serum cytokines between individuals with or without ACS or periodontal comorbidity. Material and Methods: In a case–control study, individuals with ACS (78 individuals, 10.3% females) and matching healthy controls (78 individuals, 28.2% females) were included. Medical and dental examinations were performed to diagnose ACS and periodontitis. Serum levels of cytokines were assessed, using Luminex technology. Results: A diagnosis of periodontitis in the ACS and control group was diagnosed in 52.6% and 12.8% of the individuals, respectively. The unadjusted odds-ratio that individuals with ACS also had periodontitis was 7.5 (95% CI: 3.4, 16.8, p

Publication DOI: https://doi.org/10.1111/jcpe.12540
Divisions: Life & Health Sciences > Pharmacy
Life & Health Sciences
Additional Information: This is the peer reviewed version of the following article: Widén, C., Holmer, H., Coleman, M., Tudor, M., Ohlsson, O., Sättlin, S., ... Persson, G. R. (2016). Systemic inflammatory impact of periodontitis on acute coronary syndrome. Journal of Clinical Periodontology, 43(9), 713-719, which has been published in final form at http://dx.doi.org/10.1111/jcpe.12540. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving
Uncontrolled Keywords: cardiovascular disease,cytokines,hs-CRP,human,oral disease,serum,VEGF,Periodontics
Full Text Link: http://onlineli ... .12540/abstract
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
Published Date: 2016-09
Authors: Widén, Cecilia
Holmer, Helene
Coleman, Michael
Tudor, Marian
Ohlsson, Ola
Sättlin, Susanna
Renvert, Stefan
Persson, Goesta Rutger

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