The influence of end of day silicone hydrogel daily disposable contact lens fit on ocular comfort, physiology and lens wettability

Wolffsohn, James S., Hall, Lee, Mroczkowska, Stephanie, Hunt, Olivia A., Bilkhu, Paramdeep, Drew, Tom and Sheppard, Amy (2015). The influence of end of day silicone hydrogel daily disposable contact lens fit on ocular comfort, physiology and lens wettability. Contact Lens and Anterior Eye, 38 (5), pp. 339-344.


Purpose: To quantify the end-of-day silicone-hydrogel daily disposable contact lens fit and its influence of on ocular comfort, physiology and lens wettability. Methods: Thirty-nine subjects (22.1. ±. 3.5 years) were randomised to wear each of 3 silicone-hydrogel daily-disposable contact lenses (narafilcon A, delefilcon A and filcon II 3), bilaterally, for one week. Lens fit was assessed objectively using a digital video slit-lamp at 8, 12 and 16. h after lens insertion. Hyperaemia, non-invasive tear break-up time, tear meniscus height and comfort were also evaluated at these timepoints, while corneal and conjunctival staining were assessed on lens removal. Results: Lens fit assessments were not different between brands (P > 0.05), with the exception of the movement at blink where narafilcon A was more mobile. Overall, lag reduced but push-up speed increased from 8 to 12. h (P <. 0.05), but remained stable from 12 to 16. h (P > 0.05). Movement-on-blink was unaffected by wear-time (F = 0.403, P = 0.670). A more mobile lens fit with one brand did not indicate that person would have a more mobile fit with another brand (r = -0.06 to 0.63). Lens fit was not correlated with comfort, ocular physiology or lens wettability (P > 0.01). Conclusions: Among the lenses tested, objective lens fit changed between 8. h and 12. h of lens wear. The weak correlation in individual lens fit between brands indicates that fit is dependent on more than ocular shape. Consequently, substitution of a different lens brand with similar parameters will not necessarily provide comparable lens fit.

Publication DOI:
Divisions: Life & Health Sciences > Ophthalmic Research Group
Life & Health Sciences > Optometry
Life & Health Sciences
Life & Health Sciences > Vision, Hearing and Language
Additional Information: © 2015, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Funding: Alcon Laboratories
Uncontrolled Keywords: contact lenses,daily disposables,lens substitution,objective lens fit,silicone-hydrogel,Ophthalmology,Optometry
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Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
Published Date: 2015-10
Authors: Wolffsohn, James S. ( 0000-0003-4673-8927)
Hall, Lee
Mroczkowska, Stephanie
Hunt, Olivia A.
Bilkhu, Paramdeep ( 0000-0003-3640-7681)
Drew, Tom
Sheppard, Amy ( 0000-0003-0035-8267)



Version: Accepted Version

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