Numerical simulation of corneal transport processes

Li, Long-Yuan and Tighe, Brian (2006). Numerical simulation of corneal transport processes. Journal of the Royal Society Interface, 3 (7), pp. 303-310.


This paper presents a numerical study on the transport of ions and ionic solution in human corneas and the corresponding influences on corneal hydration. The transport equations for each ionic species and ionic solution within the corneal stroma are derived based on the transport processes developed for electrolytic solutions, whereas the transport across epithelial and endothelial membranes is modelled by using phenomenological equations derived from the thermodynamics of irreversible processes. Numerical examples are provided for both human and rabbit corneas, from which some important features are highlighted.

Publication DOI:
Divisions: Engineering & Applied Sciences > Chemical engineering & applied chemistry
Engineering & Applied Sciences > Polymer and advanced materials research group
Engineering & Applied Sciences > Engineering systems & management
Uncontrolled Keywords: corneal swelling,hydration,ionic transport,electrolyte,thermodynamics
Full Text Link: https://www.ncb ... les/PMC1578740/
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
http://rsif.roy ... ontent/3/7/303# (Publisher URL)
Published Date: 2006-04-22
Authors: Li, Long-Yuan
Tighe, Brian

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